ID G0WD26_NAUDC Unreviewed; 911 AA.
AC G0WD26;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=DNA-binding protein RAP1 {ECO:0000256|RuleBase:RU367107};
GN Name=NDAI0F03690 {ECO:0000313|EMBL:CCD25687.1};
GN OrderedLocusNames=NDAI_0F03690 {ECO:0000313|EMBL:CCD25687.1};
OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD25687.1, ECO:0000313|Proteomes:UP000000689};
RN [1] {ECO:0000313|EMBL:CCD25687.1, ECO:0000313|Proteomes:UP000000689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC {ECO:0000313|Proteomes:UP000000689};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- FUNCTION: Involved in the regulation of telomere length, clustering and
CC has a specific role in telomere position effect (TPE).
CC {ECO:0000256|RuleBase:RU367107}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU367107}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367107}.
CC Chromosome, telomere {ECO:0000256|RuleBase:RU367107}.
CC -!- SIMILARITY: Belongs to the RAP1 family. {ECO:0000256|ARBA:ARBA00010467,
CC ECO:0000256|RuleBase:RU367107}.
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DR EMBL; HE580272; CCD25687.1; -; Genomic_DNA.
DR RefSeq; XP_003670930.1; XM_003670882.1.
DR AlphaFoldDB; G0WD26; -.
DR STRING; 1071378.G0WD26; -.
DR GeneID; 11497025; -.
DR KEGG; ndi:NDAI_0F03690; -.
DR eggNOG; ENOG502S85C; Eukaryota.
DR HOGENOM; CLU_014729_0_0_1; -.
DR OMA; TENAWRD; -.
DR OrthoDB; 1406561at2759; -.
DR Proteomes; UP000000689; Chromosome 6.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0010833; P:telomere maintenance via telomere lengthening; IEA:UniProtKB-UniRule.
DR CDD; cd11655; rap1_myb-like; 2.
DR CDD; cd11653; rap1_RCT; 1.
DR Gene3D; 1.10.10.2170; -; 1.
DR Gene3D; 1.20.120.1480; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR021661; Rap1_C.
DR InterPro; IPR038104; Rap1_C_sf.
DR InterPro; IPR015280; Rap1_DNA-bd.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR039595; TE2IP/Rap1.
DR PANTHER; PTHR16466; TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR16466:SF6; TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF09197; Rap1-DNA-bind; 1.
DR Pfam; PF11626; Rap1_C; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU367107};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367107};
KW Reference proteome {ECO:0000313|Proteomes:UP000000689};
KW Telomere {ECO:0000256|ARBA:ARBA00022895, ECO:0000256|RuleBase:RU367107};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 164..251
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 431..491
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 431..487
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 287..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 911 AA; 102415 MW; 0F2E116D16CFA0BC CRC64;
MSSSQNFETA PEHFVDALNS NMIDSHGDDA SHVNNTDNVN AGEPLVHVED AVSLVAANVK
VEKLKAEGAP TITDPQATQV SLVVPPTEPS SVTEPVATGN AMVDIATNGH TNGTIESGPT
SVDVSSPMSH EVGAPAVASA DGISTEAPLR TNSNTSDNGA NPVKKKLVFE NIKFFINRDS
GAIDSSTEAD QLERLITANG GEIVKALPQQ ASSDFFVVSP YNDTKLPTIT TTYIRTCIAR
DTLLPLENYL VPYDEFRAVI DSELRSLNGD GEKADQNDHI QNHVSEEQQA VEQNGLEPDQ
HDSSNTAHQE SEQKQQQQQQ QQQQQREEQL KLIHEHNIEM ENINQDIARE QLSEDQRNTS
SQPQSSLGTD MPAHIKLQHE QEQQQQQQQQ QQQQQQQQQQ QHEQNGESHV AQNRSHAYEN
SRSPLVRSPN GPTHNKSSFT ETEDEFILDV VRKNPTRRTT HTLYDEISHY VPNHTGNSIR
HRFRVYLSKR LDFVYEVDKY GKLVRDEDGN LIKTKLLPPS IKKKFTADED YALAVSVKKQ
FYRDLYQIDP DSGQSLISAQ DSPTAIARRN MTMDPNHIPG SEPGFKEYKV NDRKGPIARE
FFKSFADENP THTENAWRDR YRKFLLTFGV DAYIAYYEIE RASGREPKPM KNLTNRPKRV
NAPTPGNYNS SVKRARAYIS AKPVSNEHEQ SISNADVAAA AAAAANGQAT GPNYPIPENE
LLDEETMQFI SSLKNDLSKL ESTLPFEYPQ EIADAIRNDF TNEEEEYDNI DPNSIKFPPP
IASIELFLPT FFQMGSTREF MLKVNEVITR DYEPSQAEKL VQDLSDEAGV RRTFSTSILT
ALSGDLMVFP RYFLTMFKDN INPPPNVPGI WTREDDEMLR SNKGEDLQAL EKKHGVGRIE
IRRKFVERDL V
//
