ID   G0XS81_PRODI            Unreviewed;       785 AA.
AC   G0XS81;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Nonribosomal peptide synthetase (A-NMT) {ECO:0000313|EMBL:AEH57249.1};
GN   Name=nkdM {ECO:0000313|EMBL:AEH57249.1};
OS   Prochloron didemni P3-Solomon.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Prochloraceae;
OC   Prochloron.
OX   NCBI_TaxID=910458 {ECO:0000313|EMBL:AEH57249.1};
RN   [1] {ECO:0000313|EMBL:AEH57249.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21445351; DOI=10.1371/journal.pone.0017897;
RA   Donia M.S., Fricke W.F., Ravel J., Schmidt E.W.;
RT   "Variation in tropical reef symbiont metagenomes defined by secondary
RT   metabolism.";
RL   PLoS ONE 6:E17897-E17897(2011).
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DR   EMBL; HQ407375; AEH57249.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0XS81; -.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          13..355
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          525..623
FT                   /note="Methyltransferase type 12"
FT                   /evidence="ECO:0000259|Pfam:PF08242"
SQ   SEQUENCE   785 AA;  88565 MW;  F16F6691ED37092E CRC64;
     MNYFREKYLH KLFEKQAAKT PEAIAVSTGS RSITYKELNC KANRLANYLQ VKGIKPEMKV
     GICLERTIEM VVGVLAILKA GGAYVPLDIA YPQQRLSFML EDAKVSILLS QQKLLEKLPT
     SASPIFCFDR DWKDVIVHSD SNPIIKEMKT SILAYVIYTS GSTGKPKGVA IEHRSTLAFI
     DWAKSTFTLK ELSSVLASTS LCFDLSVFEL FVPLSVGGKV VLVENALALS AMHNLEIITL
     INTVPSVIVE LLRIKAIPSS VCTINLAGET LQAGIAERIY QETEVEKVYN LYGPTEATTY
     STFALIERGS KNLPPIGKPI NNTQVNLLDS HLNPVAYGTP GEIYISGAGL ARGYLNRPNL
     TAEKFILSPS GIRLYKTGDL GCYLSNGNLK FLKRIDHQAK IRGFRIELGE IESVLSLHHK
     VERVAVKVHQ DKANNNYLVA YIVAALQSWK SQNIDNIKDW NTQQVSRWQK VFNRLYQEVP
     KSNSTLNVIG WNNTYTGMPF SQEEMKEWID NTVKSILSLK PNRILEIGCG TGLLLFRLLD
     HCKEYCGTDI SQSTLSALKQ RIEQHHLQKV TLLERAADDF SQIAEDSFDI VVLNSVVQYF
     PNIDYLIEVL EQSLKTVAPG GFIFLGDIRS FPLLETFHAS IELYNAPPSR PTEQIKQRIQ
     KRVIQEEELF IAPAFFTSLK QRFPQISHVE ISPKSGMFDN ELTRFRYQVV IRVQREEPID
     TPVWVDWQIE QLNLEKLQCL LIEKQPDCLG VTQIPNAYLS SEAKILDELA ENQEKARTAK
     DLKKR
//