ID G1CJ05_INTLE Unreviewed; 168 AA.
AC G1CJ05;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=G protein-coupled receptor 37 {ECO:0000313|EMBL:AEL04853.1};
DE Flags: Fragment;
GN Name=GPR37 {ECO:0000313|EMBL:AEL04853.1};
OS Intellagama lesueurii (Eastern water dragon) (Physignathus lesueurii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Acrodonta; Agamidae; Amphibolurinae; Intellagama.
OX NCBI_TaxID=103694 {ECO:0000313|EMBL:AEL04853.1};
RN [1] {ECO:0000313|EMBL:AEL04853.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21787873; DOI=10.1016/j.ympev.2011.07.008;
RA Townsend T.M., Mulcahy D.G., Noonan B.P., Sites J.W.Jr., Kuczynski C.A.,
RA Wiens J.J., Reeder T.W.;
RT "Phylogeny of iguanian lizards inferred from 29 nuclear loci, and a
RT comparison of concatenated and species-tree approaches for an ancient,
RT rapid radiation.";
RL Mol. Phylogenet. Evol. 61:363-380(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JF818426; AEL04853.1; -; Genomic_DNA.
DR AlphaFoldDB; G1CJ05; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR003909; GPR37_orph.
DR PANTHER; PTHR46216:SF3; PROSAPOSIN RECEPTOR GPR37; 1.
DR PANTHER; PTHR46216; PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR01421; GPR37ORPHANR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AEL04853.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..168
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003411953"
FT TRANSMEM 67..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..168
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEL04853.1"
FT NON_TER 168
FT /evidence="ECO:0000313|EMBL:AEL04853.1"
SQ SEQUENCE 168 AA; 18875 MW; C00CA2D77FC2DBB1 CRC64;
TSTTAKLAVI WVGALLLALP EVVLRQLTKE DSEISGSPPI ERCVVKISPH LPDTIYVLAL
TYDGARLWWY FGCYFCLPTL FTITCSLVTA RKIRKVEKAC TRGNKRQIQL ESQMNCTVVA
LTILYGFCII PENICNIVTT YMSTGVSQQT MDLLHLISQF LLFFKSCV
//
