ID G1FE39_LACLL Unreviewed; 119 AA.
AC G1FE39;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Cadmium efflux system accessory protein {ECO:0000313|EMBL:QEX50201.1};
DE SubName: Full=Cadmium resistance regulator CadC {ECO:0000313|EMBL:AEK97258.1};
GN Name=cadC {ECO:0000313|EMBL:AEK97258.1};
GN ORFNames=FTN78_p010010 {ECO:0000313|EMBL:QEX50201.1}, FTN78_p020042
GN {ECO:0000313|EMBL:QEX50248.1}, PVF_pVF21p14
GN {ECO:0000313|EMBL:AEK97258.1};
OS Lactococcus lactis subsp. lactis bv. diacetylactis.
OG Plasmid pSD96_01 {ECO:0000313|EMBL:QEX50201.1},
OG Plasmid pSD96_02 {ECO:0000313|EMBL:QEX50248.1},
OG Plasmid pVF21 {ECO:0000313|EMBL:AEK97258.1},
OG Plasmid psd96_01 {ECO:0000313|Proteomes:UP000326269}, and
OG Plasmid psd96_02 {ECO:0000313|Proteomes:UP000326269}.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=44688 {ECO:0000313|EMBL:AEK97258.1};
RN [1] {ECO:0000313|EMBL:AEK97258.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DPC3901 {ECO:0000313|EMBL:AEK97258.1};
RC PLASMID=pVF21 {ECO:0000313|EMBL:AEK97258.1};
RX PubMed=21803914; DOI=10.1128/AEM.00661-11;
RA Fallico V., McAuliffe O., Fitzgerald G.F., Ross R.P.;
RT "Plasmids of Raw Milk Cheese Isolate Lactococcus lactis subsp. lactis
RT Biovar diacetylactis DPC3901 Suggest a Plant-Based Origin for the Strain.";
RL Appl. Environ. Microbiol. 77:6451-6462(2011).
RN [2] {ECO:0000313|EMBL:QEX50201.1, ECO:0000313|Proteomes:UP000326269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SD96 {ECO:0000313|EMBL:QEX50201.1,
RC ECO:0000313|Proteomes:UP000326269};
RC PLASMID=psd96_01 {ECO:0000313|Proteomes:UP000326269}, pSD96_01
RC {ECO:0000313|EMBL:QEX50201.1}, psd96_02
RC {ECO:0000313|Proteomes:UP000326269}, and pSD96_02
RC {ECO:0000313|EMBL:QEX50248.1};
RA Dorau R., Chen J., Solem C., Ruhdal Jensen P.;
RT "Complete Genome Sequence of Lactococcus lactis subsp. lactis bv.
RT diacetylactis SD96.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JN172911; AEK97258.1; -; Genomic_DNA.
DR EMBL; CP043525; QEX50201.1; -; Genomic_DNA.
DR EMBL; CP043526; QEX50248.1; -; Genomic_DNA.
DR RefSeq; WP_003726380.1; NZ_LIWD01000081.1.
DR RefSeq; YP_004770500.1; NC_015912.1.
DR AlphaFoldDB; G1FE39; -.
DR SMR; G1FE39; -.
DR GeneID; 84701732; -.
DR PATRIC; fig|1359.35.peg.2424; -.
DR Proteomes; UP000326269; Plasmid psd96_01.
DR Proteomes; UP000326269; Plasmid psd96_02.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR018334; ArsR_HTH.
DR InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; NF033788; HTH_metalloreg; 1.
DR PANTHER; PTHR43132; ARSENICAL RESISTANCE OPERON REPRESSOR ARSR-RELATED; 1.
DR PANTHER; PTHR43132:SF6; TRANSCRIPTIONAL REPRESSOR SMTB HOMOLOG; 1.
DR Pfam; PF01022; HTH_5; 1.
DR PRINTS; PR00778; HTHARSR.
DR SMART; SM00418; HTH_ARSR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00846; HTH_ARSR_1; 1.
DR PROSITE; PS50987; HTH_ARSR_2; 1.
PE 4: Predicted;
KW Cadmium resistance {ECO:0000256|ARBA:ARBA00043263};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Plasmid {ECO:0000313|EMBL:AEK97258.1}.
FT DOMAIN 23..118
FT /note="HTH arsR-type"
FT /evidence="ECO:0000259|PROSITE:PS50987"
SQ SEQUENCE 119 AA; 13382 MW; B34C01C21DC2C944 CRC64;
MNNEICEITC IHEDKVNRAK SKLANFDTPS VSGFFKILSD ENRLKIVHAL VHEDELCVCD
IANIIDASVA TTSHHLNSLK KLGVVDSHKD GKLVYYFIKN IKILNLMELG VNFKEEVLA
//
