ID G1K9L8_ANOCA Unreviewed; 292 AA.
AC G1K9L8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Isochorismatase domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040688};
GN Name=ISOC1 {ECO:0000313|Ensembl:ENSACAP00000001497.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000001497.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000001497.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000001497.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000001497.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR AlphaFoldDB; G1K9L8; -.
DR STRING; 28377.ENSACAP00000001497; -.
DR Ensembl; ENSACAT00000001533.3; ENSACAP00000001497.3; ENSACAG00000001578.3.
DR eggNOG; KOG4044; Eukaryota.
DR GeneTree; ENSGT00390000006753; -.
DR HOGENOM; CLU_047255_0_0_1; -.
DR InParanoid; G1K9L8; -.
DR TreeFam; TF313459; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000001578; Expressed in forelimb bud and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 2.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR14119; HYDROLASE; 1.
DR PANTHER; PTHR14119:SF17; ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 206..257
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 292 AA; 32266 MW; FA02C1A3DA05399C CRC64;
MAALEQHQLP AEASPSPASS SSAAAAAPLL PGGSVPVLFC FSVFARPSSV PRGSGYEALI
QKFLSLYGDQ LDMHRKFVVQ LFAEEWSQYI DLPKGFVVAE RCKVRLVPLQ IQLTTLGNLT
PSSTVFFCCD MQERFRPAIK YFGDIISVGQ RLLQGARILG IPVIVTEQYP KGLEAQFWKI
NIFYYILFCS LIYSVNICVG FFLSKTHVCI QQTALELVGR GLEVHIVADA TSSRSMMDRM
FALERLARTG IIVTTSEAIL LQLIADKDHP KFKEIQNLIK ASAPESGLLS KV
//
