ID G1KBH6_ANOCA Unreviewed; 278 AA.
AC G1KBH6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=TNF receptor superfamily member 19 {ECO:0000313|Ensembl:ENSACAP00000002986.4};
GN Name=TNFRSF19 {ECO:0000313|Ensembl:ENSACAP00000002986.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002986.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002986.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002986.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002986.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; G1KBH6; -.
DR Ensembl; ENSACAT00000003063.4; ENSACAP00000002986.4; ENSACAG00000003064.4.
DR eggNOG; ENOG502QQHI; Eukaryota.
DR GeneTree; ENSGT00940000153259; -.
DR HOGENOM; CLU_050058_1_0_1; -.
DR TreeFam; TF331385; -.
DR Proteomes; UP000001646; Chromosome 3.
DR Bgee; ENSACAG00000003064; Expressed in hemipenis and 13 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IBA:GO_Central.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IBA:GO_Central.
DR CDD; cd13418; TNFRSF19; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR022342; TNFR_19.
DR InterPro; IPR034047; TNFRSF19_N.
DR InterPro; IPR047526; TNR19/27/EDAR.
DR PANTHER; PTHR12120; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12120:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01969; TNFACTORR19.
DR SMART; SM00208; TNFR; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 152..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 57..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 57..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
SQ SEQUENCE 278 AA; 31187 MW; EC5F1438A88AB704 CRC64;
MTLKVSSNPI ICETGGCREQ EFRDRDGNCM LCEQCGPGME LSKECGFGYG EDAQCMTCRP
NRFKEDWGFQ KCKPCLDCAI VNRFQKANCS ATSNAVCGDC LPGFYRKTKL GGFQDMECVP
CGDPPPPHEP HCTAKVNLVK IPSTASSPRD TALAAVICSA LATVLLALLI LCVIYCKRQF
MEKKPTWSMR SQDVHYEGSE LSCFDRPQLN MYAHRTCCQC QRDPSQMCGA VHLIPSLCCD
ETCSLEHSCH NCTFHSRATL HERYFKFFTW AHIICCIF
//
