ID G1KD31_ANOCA Unreviewed; 894 AA.
AC G1KD31;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000004589.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000004589.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000004589.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000004589.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KD31; -.
DR STRING; 28377.ENSACAP00000004589; -.
DR Ensembl; ENSACAT00000004695.3; ENSACAP00000004589.3; ENSACAG00000004710.3.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000165528; -.
DR HOGENOM; CLU_000288_18_18_1; -.
DR InParanoid; G1KD31; -.
DR TreeFam; TF334360; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000004710; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373:SF265; LEUCINE-RICH REPEAT NEURONAL PROTEIN 1; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00369; LRR_TYP; 11.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 773..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 465..554
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 865..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..879
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 96297 MW; 46FCD9A54CDCCF5E CRC64;
MHMCLSNPIF FFSSRHDLAS WTSLSQLLTN KCPFLYPGPC GSKGSIEGIM SCLPRYALLM
LFLQAATSSL HPCPPQCVCE TRPWFTPQSV YHEARTVDCN DLLLTQVPSN LSSDTQVLLL
QSNKISQVSG ELQHLSNLTE LDLSQNHFSR ISDAGLANLS RLITLYLEEN QVEELPDHCL
SDLASLEELY INHNRISSIQ PLAFTGLTSL LRLHLNANRL RAIDHRWFLS LPNLEILMIG
ENPISQLTGG SFRPLGRLHS LVLAGMELRE VPADAFQGLD YLESLSFYDN HLPHVPTQAL
KGLPLLKFLD LNKNPIAEVR AGDFKDMLHL EELSLNGMEE LSGIHRSAFE NLPELAKLEL
CNNPRLSYFH PGAFQGVPAL RTLLMSNAAL SLLPVGLIGT LPALTELNLY GNPLRCDCLK
AWEPLGTGHI RLIESQTTLC ASPPEAAGQE LQEVLKSAMG GTCLPEIASK DLPERLEVSS
GSTVVLDCQA SSEPPPQFHW ISPSGEKLTT GSGRLHLRAG GTLEISTVNS ADAGIYTCVA
RNDFGSTSRS VALAVIGERT VSPVKLLVLA KKVQSHFVVV EWMTSFMEGQ KNERGGDSAT
PHPLATPVWS SATMRIHNPH LSYTARVPVG IREFNLTHLQ PATRYEICLT VMSSVPKSSA
AGDYTDLPTS VATSASTLTS VSSLEVGLST TGVSVSSASP LGTSRGPPAL LMAHLLATVV
SSSASKASSA PSTSPWATTT TAPPVWQLPR MQRSCLNVTT KEASLSVELV GGWAGGAALA
AVTGSLLAAL SAVLLLLCAS RRLKEKGCRH SLKKYMQHAA AIPLNEVYPP LISLWDAEGD
PPLPMAPLTQ LAPSTLPIAP PPPVTTATVG GPSLLLPPPP SQIDTSKTYL WQQP
//
