ID G1KD80_ANOCA Unreviewed; 263 AA.
AC G1KD80;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Transcription elongation factor Eaf N-terminal domain-containing protein {ECO:0000259|Pfam:PF09816};
GN Name=eaf2 {ECO:0000313|Ensembl:ENSACAP00000004718.1};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000004718.1, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000004718.1, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000004718.1,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000004718.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the EAF family. {ECO:0000256|ARBA:ARBA00007798}.
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DR RefSeq; XP_003214953.1; XM_003214905.3.
DR AlphaFoldDB; G1KD80; -.
DR STRING; 28377.ENSACAP00000004718; -.
DR Ensembl; ENSACAT00000004825.3; ENSACAP00000004718.1; ENSACAG00000004821.4.
DR GeneID; 100561868; -.
DR KEGG; acs:100561868; -.
DR CTD; 55840; -.
DR eggNOG; KOG4795; Eukaryota.
DR GeneTree; ENSGT00390000017724; -.
DR HOGENOM; CLU_025755_1_0_1; -.
DR InParanoid; G1KD80; -.
DR OrthoDB; 318263at2759; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000004821; Expressed in adrenal gland and 13 other cell types or tissues.
DR GO; GO:0032783; C:super elongation complex; IEA:InterPro.
DR GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0003711; F:transcription elongation factor activity; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR027093; EAF_fam.
DR InterPro; IPR019194; Tscrpt_elong_fac_Eaf_N.
DR PANTHER; PTHR15970:SF7; ELL-ASSOCIATED FACTOR 2; 1.
DR PANTHER; PTHR15970; ELL-ASSOCIATED FACTOR EAF; 1.
DR Pfam; PF09816; EAF; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..112
FT /note="Transcription elongation factor Eaf N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09816"
FT REGION 130..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 263 AA; 28992 MW; 5E4DAD51179A5489 CRC64;
MNGAAPPLFD CKERVLRLGH SFERQPRCAF HTVRYDFKPA SIDTSSEGDL EVGKGEQVTI
TLPNIEGSTP PVTVFKGSKK PYQKECILII NHNTGECRLE KLSSNITVKK TRGEGSSKVQ
SRIEQQQQLM RNANRIPNNV KFSPQKEKMS PPSLMDDIER ELKAEAKIIE EMSSSGSSSE
SKSSSSSSNS DNSSSDSEDE GAKPSFPLSM SHRHSQPPTT MVSQQVFPDI DAGYHRSQEG
SGHLMNTLRN DLQLSETGSD SDD
//
