ID G1KGZ3_ANOCA Unreviewed; 513 AA.
AC G1KGZ3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Adhesion molecule with Ig like domain 3 {ECO:0000313|Ensembl:ENSACAP00000007576.3};
GN Name=AMIGO3 {ECO:0000313|Ensembl:ENSACAP00000007576.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000007576.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000007576.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000007576.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000007576.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. AMIGO family.
CC {ECO:0000256|ARBA:ARBA00005670}.
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DR RefSeq; XP_008103221.1; XM_008105014.2.
DR AlphaFoldDB; G1KGZ3; -.
DR STRING; 28377.ENSACAP00000007576; -.
DR Ensembl; ENSACAT00000007737.3; ENSACAP00000007576.3; ENSACAG00000007744.3.
DR GeneID; 103277912; -.
DR KEGG; acs:103277912; -.
DR CTD; 386724; -.
DR eggNOG; ENOG502QUWU; Eukaryota.
DR GeneTree; ENSGT00950000183146; -.
DR HOGENOM; CLU_030478_0_0_1; -.
DR InParanoid; G1KGZ3; -.
DR OrthoDB; 5352422at2759; -.
DR TreeFam; TF326838; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000007744; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007420; P:brain development; IBA:GO_Central.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR031283; AMIGO.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24368; AMPHOTERIN-INDUCED PROTEIN; 1.
DR PANTHER; PTHR24368:SF62; AMPHOTERIN-INDUCED PROTEIN 3; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00409; IG; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..513
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003413308"
FT TRANSMEM 389..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 262..367
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 513 AA; 58595 MW; 787E62FD6400E3E4 CRC64;
MNVLTLAIPI WKFLGKLLFF ELCIQLSNLN KLYVLANCPD GCICTADLLS CANQSLEQVP
VTLPPTTTTL DLSHNNIAWI NGNWLSALPR LQTLRISHNK INNISRKVFY HATDLAHLDM
SSNCLHIVEG YYFEGLVNLK ELLLYNNKII QVDENAFVKL TSLRKVYLSW NRLTKFPFEF
IQRLEHPYLR TLDLSTNNLS TIPVEIIRSL PRYVKNGLYL HNNPVKCDCS VHQMFQEWKH
HGFSSVKDFI EEHTCKIYAH EPRSLLKTFK YNEYFDHCSE NQRKAAIPEV NCKVGDSLII
DCNTGFHEDN TTTYQWFSPR YELFMYLKHT DKTHQLFKNG SLKIINAKTL HSGVYVCIAI
SEDRKINRTH KVNVTVQYPK PVESFNTGLT TLLGCVVSLV LVLLYLYITP CYCSKCCKKS
VKPPQDCSAQ SSILSTTPPP LNRKISANKH VVFLEPIKER QNGKVKLAVS EDFPDAKSPT
FLQLKLDTES SSSAFSDLPF TSYEARAHSP ANG
//
