ID G1KHN5_ANOCA Unreviewed; 244 AA.
AC G1KHN5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Leucine rich repeat containing 3 {ECO:0000313|Ensembl:ENSACAP00000008185.3};
GN Name=LRRC3 {ECO:0000313|Ensembl:ENSACAP00000008185.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008185.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000008185.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008185.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000008185.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G1KHN5; -.
DR STRING; 28377.ENSACAP00000008185; -.
DR Ensembl; ENSACAT00000008361.3; ENSACAP00000008185.3; ENSACAG00000008369.3.
DR eggNOG; KOG4237; Eukaryota.
DR GeneTree; ENSGT00940000154360; -.
DR HOGENOM; CLU_064640_0_0_1; -.
DR InParanoid; G1KHN5; -.
DR OrthoDB; 5397338at2759; -.
DR TreeFam; TF327070; -.
DR Proteomes; UP000001646; Chromosome 3.
DR Bgee; ENSACAG00000008369; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IBA:GO_Central.
DR GO; GO:0099104; F:potassium channel activator activity; IBA:GO_Central.
DR GO; GO:0044325; F:transmembrane transporter binding; IBA:GO_Central.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 3.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..244
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032379758"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..60
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
SQ SEQUENCE 244 AA; 27987 MW; 535573104DC27091 CRC64;
WPMLWFCSQA LFFLLFCVPS YCTSCPEQCQ CTNYSEATAV LCSASNLQEI PRDIPKDTMF
LKLDANKITA VPNSTFRHLA HLQEIDLSKN AIEKIDSAAF KGVADGLRLL DLSGNHIQRI
PKEALVNLNA MIRLSNNPWH CECTLQEVLW EVKLDPDSVN ETTCQTSVQE EYTGKPLLHI
LDSRFCNMHQ KTTDVAMFVT MFSWFTLVIS YVVYYVRHNQ EDTRKHLEYL KSLPSTRVPK
ETIS
//
