ID G1KNG3_ANOCA Unreviewed; 874 AA.
AC G1KNG3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=SMC5-SMC6 complex localization factor 1 {ECO:0000313|Ensembl:ENSACAP00000013011.4};
GN Name=SLF1 {ECO:0000313|Ensembl:ENSACAP00000013011.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000013011.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000013011.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000013011.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000013011.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KNG3; -.
DR STRING; 28377.ENSACAP00000013011; -.
DR Ensembl; ENSACAT00000013270.4; ENSACAP00000013011.4; ENSACAG00000013255.4.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG1929; Eukaryota.
DR GeneTree; ENSGT00940000158953; -.
DR HOGENOM; CLU_010529_0_0_1; -.
DR TreeFam; TF329705; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000013255; Expressed in forelimb bud and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0035861; C:site of double-strand break; IBA:GO_Central.
DR GO; GO:0006974; P:DNA damage response; IBA:GO_Central.
DR GO; GO:2000781; P:positive regulation of double-strand break repair; IEA:InterPro.
DR GO; GO:1990166; P:protein localization to site of double-strand break; IBA:GO_Central.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR042479; Slf1.
DR PANTHER; PTHR46677; SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1; 1.
DR PANTHER; PTHR46677:SF1; SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF16770; RTT107_BRCT_5; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT DOMAIN 17..95
FT /note="BRCT"
FT /evidence="ECO:0000259|SMART:SM00292"
FT REPEAT 680..713
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 748..772
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 637..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 212..239
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 637..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 874 AA; 100132 MW; 4DEEAE181D5F016C CRC64;
MFCVTIIVHL LSKQMENGML QPRIIQLTGF KNQEKKILVE LLLKLESIFY DTKQYRNCTH
LIAKQPCKSE KFLAACAAGK WILTKDYIIN SAESGRWLDE TTYEWGYKIE KGSHYSPQMQ
SAPKRWREEL TCSGAAGAFH RWKVLLVIKG DKRKDSLIRV LDAGKATIHA ALSSPKNITH
VLTNYATLDQ EREKVFGTRS YPVRYLETYL FKNEIKHDLE KYQENSLQKE QEFKEIMTDI
HCGKMRSELI KHIYFQQAML SKYTQIDQMN GCRKEVKNIR YSRGENSILE ELVDDQLFPT
AVREFFSGRA LVPPAKFLQS LLGHLLQGNS DPALSAQFFH ILYTLLQHAP PWKSPSMLRY
YLEVLQCPVS MKGAWPLMET LVRSCLYCKS ICHSVPVSET MNEEKTFHKS LLRFILNLFQ
AEVLTLTRSL YEGVGSQRLQ TMPETVLQKT FWLESESMLL TKRINILVDW VTNSYKEKYK
TNDIFKHEVV ELLNGILSTV VEYWILSGFM MDKNMLHLVA DELASYIAIS CDDFSAEELK
AFVSSIPSLW LEMFVAEAVF KKLYFETSTV ISDEPLSLQK IVCSYLPALQ IWMRETGKMQ
KGKREKIGQW PCPESQRALL MLNGDKQNQA EVLPDVPAQT RTSSPPPKKF KTKTEIQSSH
GKKIYQSSPK QMNIYKVNVK GETALHITCK SNNVKKLIHL LSLPGIDINV KDYAGWTPLH
EACNHGSTVC VHEILQHCPE VNLFSQVDGV TPLHDALTNG HIEIAELLLQ HGGLALLEQK
DSEGNLPLDH IKCVRTKQHL LNVAKSEETI EEFHARVESS WNSQQTEFWT ALFCKMLLNF
CSVYNLFRPL SVSFKKSACS KPFLVTAGCC SVLI
//
