ID G1L2Z2_AILME Unreviewed; 1157 AA.
AC G1L2Z2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=RNA binding motif protein 33 {ECO:0000313|Ensembl:ENSAMEP00000001252.2};
GN Name=RBM33 {ECO:0000313|Ensembl:ENSAMEP00000001252.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000001252.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000001252.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000001252.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1L2Z2; -.
DR STRING; 9646.ENSAMEP00000001252; -.
DR Ensembl; ENSAMET00000001304.2; ENSAMEP00000001252.2; ENSAMEG00000001198.2.
DR eggNOG; ENOG502QR1Z; Eukaryota.
DR GeneTree; ENSGT00530000063891; -.
DR HOGENOM; CLU_008001_0_0_1; -.
DR InParanoid; G1L2Z2; -.
DR TreeFam; TF332363; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0106222; F:lncRNA binding; IEA:Ensembl.
DR GO; GO:1990247; F:N6-methyladenosine-containing RNA reader activity; IEA:Ensembl.
DR GO; GO:0035553; P:oxidative single-stranded RNA demethylation; IEA:Ensembl.
DR GO; GO:0043488; P:regulation of mRNA stability; IEA:Ensembl.
DR GO; GO:0006405; P:RNA export from nucleus; IEA:Ensembl.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR039878; RBM33.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR22014; RNA-BINDING PROTEIN 33; 1.
DR PANTHER; PTHR22014:SF2; RNA-BINDING PROTEIN 33; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 1086..1153
FT /note="RRM"
FT /evidence="ECO:0000259|SMART:SM00360"
FT REGION 1..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 907..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..329
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..436
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..505
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..567
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..622
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 761..786
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1157 AA; 127723 MW; 6F65A97D298EC027 CRC64;
MAAALGAGGG AGAGDDDFDQ FDKPGAERSW RRRAADEDWD SELEDDLLGE DLLSGKKNQS
DLSDEELNDD LLQSDNEDEE NFSSQGVTIS LNTTSGMVTS FELSDNTNDQ SGEQESEYEQ
GEDELVYHKS DGSELYAHEY PEEGQYEGHD AELTEDHMEY VEEPEEEQLY NDEVLDIEIN
EPLDEFTGGM ETLELQKDVK EESDEEDDED EESGRLRFKT ERKEGTIIRL SDVTRERRNI
PETLELSAEA KAALLEFEER ERQHKQGRYG SRRGGRRGGP VVCRGMGDQR RENSERARIK
DHRPALLPTQ PPGVPQPPPP PPPPPQQPIR SLFQQQQLQP LLPLQHPHHA SPPQGVHLPP
QIEAPRVMMT PPPVTPQQPK NIHINPHFKG AVVTPVQVPL LPVPSQPRPA VGPQRFPGPP
EFPQHTPGPV PSNFSQPPRL PLQDQWRAPP PPQERDPFFL GVSGEPRFPS HLFLEQRSPP
PPPPPPTLLS STHPVPTPSP LPFTQPGPAF NQQGQQPVFP RERPVRPTLQ PPGPVGILHF
SQPGSAATRP FIPPRQPFLP GPGQPFLPAH AQPNLQGPLH PPLPPPHQPQ PQPQQQPPLQ
PQHQPPLQPP PQHQPPPQPP HQPQHQHHHH LSVPPPPLMP MSQPQFRPHV QTAQPPPSSG
RMQCPQRQGL RHNTTSQNVT KRPMQPMQPT APRNSNLREL PIAPSHVMEM SSSRCSSTPA
APGKPVASTS PPTRPGGGPR GAQGKSEAKV KPVSPVVQPK EEAKTEPEFP DEDEETRLYR
LKIEEQKRLR EEILKQKELR RQQQAGARKK ELLERLAQQQ QLHLPPAAAE QERPVASPSP
TNGNPLLPFP GAQVRQNVKN RLLVKNQDVT VSNVQPKTSN FVPSGANLQY QGQQMKPLKH
LRQARTVPQS PAQHKVLQVK PADGEGPPPP SQTARVASLQ GRPPDAKPGA KRTVMHRANS
GGGDGPHVSS KVRVIKLSGG GGESDGFFHP EGQPQRLPQP PEVRQQPARK VTLTKGALQQ
PQHPPVGPHV HSAGPPAIKS IQGVHPAKKV LMHGRGRGVA GAMGRGRLMP NKQNLRVVEC
KPQPCVVSVE GLSSSTTDVQ LKNLLMSVGP IQSLQMLPQQ RKAIAKFKEP AHALAFQQKF
HRHMIDLSHI NVALIVE
//
