ID G1L9N0_AILME Unreviewed; 535 AA.
AC G1L9N0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Leucine rich repeat containing 53 {ECO:0008006|Google:ProtNLM};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000003603.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000003603.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000003603.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1L9N0; -.
DR STRING; 9646.ENSAMEP00000003603; -.
DR Ensembl; ENSAMET00000003744.2; ENSAMEP00000003603.2; ENSAMEG00000003421.2.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000161095; -.
DR HOGENOM; CLU_041090_0_0_1; -.
DR InParanoid; G1L9N0; -.
DR TreeFam; TF341942; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF161; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 53; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 6.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..535
FT /note="Leucine rich repeat containing 53"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030170663"
FT TRANSMEM 293..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 535 AA; 59182 MW; 8C5DCC483D7DC51C CRC64;
MVLRLVAACP ASCVVCARDV TLCQQLTYIV AAPVTTRVLI VTDGNLSSIE STNLSLLFNL
ALLSLSRNGI EDVQEDALHG LSKLRTLLLE HNQISSSSLT DRTFSKLQGL RVLVLSNNAL
RSLRGSWFRN TKGLTRLQLD GNQITNLTGS SFGGTKLHSL RHLDLSNNFI SYIGKDAFQP
LPQLQEVDLS RNRLAHIPDV FTPLKQLILL SLDKNRWSCS CDLYPLARFL RNYVKSSARV
LRNAKDLSCQ PSAAAVAPAQ SVLRLSETSC DSKVSNFTLV LKDRSPLLPG QDVALLTVVG
FAGAVGLTCL GLVVFNWKLR QGKANEHTSE NLCCRTFDES LCAHEARNYH AKGYCNCHLT
QGNELKVMST VGSRKETPLL RENSHQAALA SESTALDGSF RNLKGKDHGA DSTFFCFGGR
LLQSGCAEPP GNMAAFNEAG LLTRYCPKRV KKLRNHEPGE VQPQTLPQHV TRTIDINGDT
FSRRYATSAS MLARKSLEKP LTNESWQFQY INQDHTDDLK RQQKRNAANL GKWKK
//
