ID G1LTW0_AILME Unreviewed; 583 AA.
AC G1LTW0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Cyclic nucleotide binding domain containing 2 {ECO:0000313|Ensembl:ENSAMEP00000010508.1};
GN Name=CNBD2 {ECO:0000313|Ensembl:ENSAMEP00000010508.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000010508.1, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000010508.1, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000010508.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_002916462.1; XM_002916416.3.
DR AlphaFoldDB; G1LTW0; -.
DR STRING; 9646.ENSAMEP00000010508; -.
DR Ensembl; ENSAMET00000010964.2; ENSAMEP00000010508.1; ENSAMEG00000009986.2.
DR GeneID; 100464813; -.
DR KEGG; aml:100464813; -.
DR CTD; 140894; -.
DR eggNOG; KOG1113; Eukaryota.
DR GeneTree; ENSGT00390000003964; -.
DR HOGENOM; CLU_033437_0_0_1; -.
DR InParanoid; G1LTW0; -.
DR OMA; IMMIRVC; -.
DR OrthoDB; 5397097at2759; -.
DR TreeFam; TF326269; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030552; F:cAMP binding; IEA:Ensembl.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR InterPro; IPR043533; CNBD1/2.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR23011:SF44; CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR23011; UNCHARACTERIZED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 116..218
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 243..292
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 583 AA; 68250 MW; 8A3A9368A9FC4D64 CRC64;
MRRYMVSYSW QILKKELGLY QLTMDIIVMI RVCKIFRQGL RGFREYQIIE TAHRKHPLFS
FWDKRKQGRI TFDTMDFVAE EGHFPPKAMQ IAQKLPSWRT EPEIQALCNL LQVLDSYRNY
SEPLQLLLAK VMRFERFGRR RVIVKKGQRG NSFYFIYLGT VAVTADDDGS SAFLDTHPTL
LHKGDCFGEL GVLTPSVRRA TVVCMEETEF LVVDREDFLA NKLDQEFQKD AQHQFEFFRK
MDLFESLSDE KLWKLVTLGK VEKFPYGQLI SKDFVESSSI MFVSKGSCEV LRLIDLGTSP
FYYKWIWQHL DLLYDRPLKT HLNESSPVER FKEFQIKSYP VQDFSFLKLK HLQNSWEQQR
TSLSRRMNTS GNTLPKMLGP KIKSRNLHLL ECSMISTKYG DLPEEAAVGA YIKVHTVEEG
ETVGLHQILL PENQQDMRPL ILVSLGAEVI RVRKEKFCEL IDSKVTEKLS RFKVNYPSDE
DMCQKFLQEN SWNIFRKDLQ RLLVKPRQRP PFTPIRPKKK GIYSPKSLIL DLCSFNKEPK
PCHPVFMAPQ KYLPPLRIVQ AITAPRYKIQ ELLPQYKNAG VLV
//
