ID G1N0Q2_MELGA Unreviewed; 1015 AA.
AC G1N0Q2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000005024.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000005024.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000005024.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; G1N0Q2; -.
DR Ensembl; ENSMGAT00000005750.2; ENSMGAP00000005024.2; ENSMGAG00000005116.2.
DR GeneTree; ENSGT00950000183101; -.
DR HOGENOM; CLU_017821_0_0_1; -.
DR InParanoid; G1N0Q2; -.
DR TreeFam; TF332598; -.
DR Proteomes; UP000001645; Chromosome 21.
DR Bgee; ENSMGAG00000005116; Expressed in spleen and 17 other cell types or tissues.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 3.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR PANTHER; PTHR24043:SF0; SCAVENGER RECEPTOR CLASS F MEMBER 1; 1.
DR Pfam; PF00053; Laminin_EGF; 2.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00180; EGF_Lam; 5.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645}.
FT DOMAIN 199..238
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 61..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..810
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 228..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1015 AA; 108547 MW; 489F0E396DEDABE6 CRC64;
MVSGQQQQRP PHTQLLRSLG NHRLTGHTAG AGGRAQTRAS HTSTLTLLDL TMASPAATEH
SVVHSWDAQP AQSSSAPPGT LPHPAPPKVR NRQGRGILCL LLPPAPLAWG WDASSRVSSG
RNQGWREEEA EPQERNPRTD RRMDRRSPGR MASTHLLLCL QLWLWVQGSA QELDPNGRNV
CKVGSPAVNL ACCPGWKQEG RECTAALCEG EDACGPREVC VRPGLCRCKP GFFGADCSSP
CPAQYWGHDC KRLCLCHPGG TCEAESGRCT CNPERWGELC QFRCPCGPHG RCDPTTGACR
CEQGWWGPDC KRQCQCNLAT SRCDPLTGHC HCRLGWWGRK CRFKCSCNLS PCVQETGNCK
CKAGFWGSAC QWHCDCLHGS CNPLNGHCSC EPGFQGRSCQ DPCPAGMYGS QCVHSCGNCK
HNQPCSSVDG FCLECQPGWN GTLCKERCMP GFHGQGCLQP CPHCRQGDIC DAETGSCPRC
EPGWTGPSCN SSCPAGTFGD GCQLLCPECV WGSCDPVSGD CLCQAGYWGA SCNDTCPEGF
FGVNCSSPCQ CSRGTCHPAQ GNCILSVTDH AALAAAILIP LLLLLLCVVC CCCGAGPADA
RDRAAVPDDD VVARMKHHVH VVLANISAMM PCFALNNSKL PKVTVSHHDA EIPFNPSFIE
SPSAAWASDS SFSSFDTDNE GPEYSVPPRE GVPLLSGAEL QAGMPPPSEA LPDPTAFSSE
DVSQPFTIPR TSSIAKAKRP SVSFAEGTKF STAETPSPGR KPKAMWGPSK LSLQSGDVGT
EISAEQAASD GYESPDPLSK GDESHRPSPR ATPGGRRRMI TNTRHVAQRV EALEAAAKRG
SWDGKRKEPN VTTIYMTVGT AGQDPKAEGG VEGPVQAVLK RLGSLQRGRW AAKEEPMVRR
SMEGIQKPPR RALAQRRDSA NGCKQRESVP GAPGELCPGK EQHPPGKRQS FPLESTKSTG
GQDGVGEGLG AAERGKSLEL ALSVETKGQV AQEEEPKYEN VSSRNEDAPT NPATT
//
