ID G1N6N8_MELGA Unreviewed; 617 AA.
AC G1N6N8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN Name=KLHL8 {ECO:0000313|Ensembl:ENSMGAP00000007772.1};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000007772.1, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000007772.1, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000007772.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003205619.1; XM_003205571.3.
DR AlphaFoldDB; G1N6N8; -.
DR Ensembl; ENSMGAT00000008554.2; ENSMGAP00000007772.1; ENSMGAG00000007610.2.
DR GeneID; 100542470; -.
DR KEGG; mgp:100542470; -.
DR CTD; 57563; -.
DR GeneTree; ENSGT00940000157583; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; G1N6N8; -.
DR OMA; YRAAIKW; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000001645; Chromosome 4.
DR Bgee; ENSMGAG00000007610; Expressed in liver and 17 other cell types or tissues.
DR CDD; cd18448; BACK_KLHL8; 1.
DR CDD; cd18238; BTB_POZ_KLHL8; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 3.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 64..131
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 68259 MW; 995CF523456F196E CRC64;
MASESMVPEQ GKQHPVKGKR RPQQQQTRSS SGDGEDDIFV FEANEAWKDF HSSLLHFFEA
GELCDVTLKV GTKLISCHKL VLACVIPYFR AMFLSEMAEA KQTLIEIRDF DGDAIEDLVK
FVYSSRLTLT VDNVQPLLYA ACILQVELVA KACCEYMKLH FHPSNCLAVR SFAESHNRID
LMDMADQYAC EHFTEVVECE DFVSVSPQHL HKLLSSSDLN IENEKQVYSA AIKWLLANPQ
HHATWLDEIL AQVRLPLLPI CFLMGVVAKE EIVKQNLKCR DLLDEARNYH LHLSSRAVPD
FEYSIRTTPR KQTAGVLFCV GGRGGSGDPF RSIECYSINK NSWFFGPEMN SRRRHVGVIS
VGGRVYAVGG HDGNEHLGSM EVFDPLTNKW MIKASMNTKR RGIALASLGG PIYAIGGLDD
NTCFSDVERY DIESDRWSAI APMNTPRGGV GSVALMNHVY AVGGNDGIAS LSSVEKYDPH
LDKWMEVKEM GQRRAGNGVS ELHGCLYVVG GFDDNSPLSS VERFDPRSDK WEYVAELTTP
RGGVGIATLM GRIFAVGGHN GNAYLNTVEA FDPIVNRWEL VGSVSHCRAG AGVAVCACLS
SQIRDVGQGS SNVVDCM
//
