ID G1N8B1_MELGA Unreviewed; 690 AA.
AC G1N8B1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Protein DBF4 homolog A {ECO:0000256|ARBA:ARBA00040397};
GN Name=DBF4 {ECO:0000313|Ensembl:ENSMGAP00000008530.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000008530.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000008530.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000008530.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_019471921.1; XM_019616376.1.
DR AlphaFoldDB; G1N8B1; -.
DR Ensembl; ENSMGAT00000009329.2; ENSMGAP00000008530.2; ENSMGAG00000008326.2.
DR GeneTree; ENSGT00530000063909; -.
DR HOGENOM; CLU_030726_2_0_1; -.
DR InParanoid; G1N8B1; -.
DR TreeFam; TF332790; -.
DR Proteomes; UP000001645; Chromosome 6.
DR Bgee; ENSMGAG00000008326; Expressed in bursa of Fabricius and 18 other cell types or tissues.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.40; -; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF22; PROTEIN DBF4 HOMOLOG A; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00600}.
FT DOMAIN 276..324
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 83..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 77996 MW; 7ED458EC75E30490 CRC64;
MQAKTEKIKS SLKSVKKEVG KPEKLKYKPL TGKVFYLDIP SNVISEKIGK DLKDLGGRVE
SFLSKDISYL VSSKKEAKFA PTLSQISPVP SPESVCNGGN DTSHPSKRKD RQDGSSFKAA
DAVRLSRGKS LAEKAIREQE LIPSGSMLSN ALSWGVKVLH IDDVKHYIEQ KKKELYLIKS
TGSSFKDVGK QVTTQKSKSR LKNPFVKVED RSRSYRPFYL QLPSFPALNY CVPKPCSPFE
VDKKHPPGQK QTQSKQRKDM NSDKDCKTPV QLHQKDKKRR GYCECCGKKY EDLQTHLKSE
QHQNFAQSAQ YQVVDDIISK FVYEFVEYRD DEKNMKRIKC STGYFSPIIG KITRPDELKE
RLKKQRISLK TYSWKDTTMQ ALKLDCQPAE VQPNSVLVPT PVSASLCSIL YCHLSQPPEV
KSKFRNNGGN TRTNCFCATN LGQSVMSPNF IQPLPQKDGK SYMENSCQDY EPFSKEILEP
EVSKKNLQHF QEGVCTLCSH TQVTDFSEKD KNLAQPKRKL NPAVVLPAKC LKKTDANPTF
VEKHRDLCDN HQQMQHNVVL EAEVSESAIN KELNELAANA AHCSPSGKLH RKVKLCLGRN
RRENRKQNIE LCVKYADGLS VPREKRDCSS PVQALLELFQ TSEIKSEFRG FSVYTDHQDS
TGTEDVWEGL NTNVVSSLFS SSSSSPFVGF
//
