ID G1NB28_MELGA Unreviewed; 1145 AA.
AC G1NB28;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=RNA binding motif protein 27 {ECO:0008006|Google:ProtNLM};
GN Name=RBM27 {ECO:0000313|Ensembl:ENSMGAP00000009786.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000009786.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000009786.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000009786.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in the turnover of nuclear polyadenylated
CC (pA+) RNA. {ECO:0000256|ARBA:ARBA00043866}.
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DR Ensembl; ENSMGAT00000010621.3; ENSMGAP00000009786.3; ENSMGAG00000009467.3.
DR GeneTree; ENSGT00510000046929; -.
DR HOGENOM; CLU_031853_0_0_1; -.
DR InParanoid; G1NB28; -.
DR Proteomes; UP000001645; Chromosome 15.
DR Bgee; ENSMGAG00000009467; Expressed in bursa of Fabricius and 17 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd12517; RRM_RBM27; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045137; RBM26/27.
DR InterPro; IPR034451; RBM27_RRM.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF1; RNA-BINDING PROTEIN 27; 1.
DR Pfam; PF01480; PWI; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 417..445
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 670..744
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1031..1100
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT ZN_FING 417..445
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 248..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1100..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..326
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..484
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..506
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1110..1138
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1145 AA; 127522 MW; C3945D70C49F9FBE CRC64;
MMAMNAKQPF PMHSALQEPK YSGLHAGAEA MRRVCLPAPQ LQGNIFGSFD ESLLARAEAL
AAVDIVSHAK SHPFKPDATY HAMSGVPCGP AAXXXXXXXX XXXXXXXXXX XXXXXXXXXX
XXXXXARGAS TACANCWGLT GPSHLSYCGA AAVSTKGRNV CDADPSALAN YVVALVKKDK
PEKELKAFCA DQLDVFLQKE TSGFVDKLFE SLYTKSYLPS HEPTKVEVKP AGQEKEVIKE
ELSVKQNFQE SVEEERDSRK KKHSSPQRSR ADSSEQRTRE KRRDDGKWRD YDRYYDRSDL
YREKSSWRRG RSKSRSKSRG LSRSRSRSRG RSKDHDASRS VEHRERSKFK SERNDVEGTY
NAVSASASNS TEQYSAAQSI PSAVTVIAPA HHLENTTESW SNYYNNHSNP SSFGRNPPPK
RRCQDYDERG FCVLGDLCQF DHGNDPLVVD EVSLPSMIPF PPPPPGLPPP PGMLLPPMPG
PARSLRIPVP QAHPQAPPPV VLPVPRPPLT QSSLINSREQ PGTSAVPSLA PVGARLPPPL
PQNLLYTVSE HTYEPDGYNP EAPSITSAGR SQYRQFFTRA QTQRPNLIGL TSGEMDTNPR
AANIIIQTEP PIPITNNSSN VTRVVLEPDS RKRSPSSLEC PPLKKPWLGK QANNNQNKPG
FLKKNQYTNT KLEVRKIPPE LNNITQLNEH FSKFGTIVNI QVAFQNDPEA ALIQYLTNDE
ARKAISSTEA VLNNRFIRVH WHREGEQQPP LLQQQQQQSP SQALHHQLHL QQQALTPAPA
VTMHSNLSKA VNKPLASGAY VLNKVPVKRR LGAAGNQPDL SQTGAVVEDC QTFPTPTSHS
KMVYSSSNLK AAMKPGAGSK PHDVQEALKK KQEAMKLQQD MRKKKQEMLE KQIECQKMLI
SKLEKNKAMK PEERAEIMKT LKELAGKISQ LKDELKTSST TSTPSKLKSK TEAQKELLDA
ELDFHKRLSS GEDTTELRKK LNQLQVEAAR LGILPAGRGK TVPAQGRGRG RGRGGRGRGV
LNHMVVDHRP KALTVGGFIE EEKDELLQHF SKFGDIEDLQ EEDSPLSVVL TFKSRSEAEN
AANQGSKFKD RRLQISWYKP KVPSVSTEVE EEESKEEETE TSDLFLHEDD DDEDEDEDES
RSWRR
//
