ID G1NFQ9_MELGA Unreviewed; 1272 AA.
AC G1NFQ9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Plexin C1 {ECO:0000313|Ensembl:ENSMGAP00000011862.3};
GN Name=PLXNC1 {ECO:0000313|Ensembl:ENSMGAP00000011862.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000011862.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000011862.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000011862.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G1NFQ9; -.
DR Ensembl; ENSMGAT00000012744.3; ENSMGAP00000011862.3; ENSMGAG00000011352.3.
DR GeneTree; ENSGT01020000230394; -.
DR HOGENOM; CLU_389767_0_0_1; -.
DR Proteomes; UP000001645; Chromosome 1.
DR Bgee; ENSMGAG00000011352; Expressed in spleen and 14 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd00102; IPT; 1.
DR CDD; cd00603; IPT_PCSR; 1.
DR CDD; cd12789; RasGAP_plexin_C1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF4; PLEXIN-C1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00423; PSI; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 647..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 789..810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..179
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 1272 AA; 145016 MW; 0DF7D96D7ACDF551 CRC64;
MVVMHQPHRS EHSFDLQGQV YLDCGCRSLL ISSSLIRQEE RGWWVGVFHH NHGDRAWDST
AVCVFRMEEL QDPTCVYITH FYSGTNCKVQ SIKKSPTLIH SGLVAVYGTV VLNQIVLFLG
TDDGQLLKAI LNEDMKSNCP EILYEIEEET SIFPKLRLDP VDSNYIYLFS ANKVRRIPVA
NCGRYVSEQE CLSAKDPYCG WCSLNQRCTL KENCTRSNST KGWFNISHAP DKDLKILLRF
PARNQISVSA SISKTLTSCI IKIVKPIEMP HENVVLKNSS CVCSLATSVI LDHDCLVLEA
SLSSNSWNIT ETFQLENCSR CIHDGECASC NWTRVSPATA CQDICSVQNS SKDIITAQKS
EHINIHSIEP LWISTLGKSE ITVKGENFTH ASGIKLILTG SSGCKQEIIK VRNVINDTQM
TFALPPMRKE AKSVCIQADG RKCSPPVTLH YVSLPACFGI TPNTSWISGG RKITTTGRNL
NVVDKVIISD DQRSNLTISE YPQNKSEYHY LSPSLSHATE GKVVDMIFKV ETTFVPCVKL
HYHPDPVFIN YQLHTELDPD LELKIYKEND NLNISKTEVE VYLSYMNGSQ TAKIYFSVQN
ITEKPDRSTI LCKFKREGTE KIDFSTVKVF VKLGNFELEV KPTSSYIYLY VLILLPIVVG
VIIVAFIVTR YKSKELTRKQ SQQLELLEYE IRKEIREGFA ELQMDELDVV DSFGTVPFLD
YKHFAIRTFF PESGGFASIF SEDIPQSRDQ TRKDESFNML HALICNKNFL VTLIHTLEKQ
KNFSVKDRCL FASFLTIALQ TKLVYLTHIL EVLTKDLMEQ SSNVQPKLLL RRTESVVEKL
LTNWMSVCLS GFLRETIGEP FYLLVTTLNQ KINKGPVDAI TCKALYTLNE DWLLWQVSEF
KTVTVNVIFE KIPENESGDA CQTIQVNVLD CDTIGQTKEK SLQAFLNKNG FPYGLQLNEI
GLELVSEEQQ RELLDIDGSS EMIEDGIRKL NTIAHYKIAN GATIKILKKM TNTRSDVDYS
DEHCHLILPD SEANKDMKGS GHKGKQKFKV KEMYLTKLLS TKVAIHSVVE NLFRSIWSLP
NNKAPVAIKY FFDFLDTQAE NKRITDPDVV HIWKTNSLPL RFWVNILKNP QFVFDVKKTS
HIDGCLSVIA QAFMDAFSLA EQTMGKEAPT NKLLYAKDIP LYKKEVKAYY KAIRDLPPLT
TSEVEEFLTQ ESKKHENEFN EEVALMEIYR YIVKYYDEIV SKLERERGFE DVQKQLQQVK
ALFDEKKKCK WV
//
