ID G1NYY0_MYOLU Unreviewed; 331 AA.
AC G1NYY0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Glycerophosphodiester phosphodiesterase 1 {ECO:0000313|Ensembl:ENSMLUP00000002642.2};
GN Name=GDE1 {ECO:0000313|Ensembl:ENSMLUP00000002642.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000002642.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000002642.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000002642.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000256|ARBA:ARBA00007277}.
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DR EMBL; AAPE02016517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006088259.1; XM_006088197.2.
DR AlphaFoldDB; G1NYY0; -.
DR STRING; 59463.ENSMLUP00000002642; -.
DR Ensembl; ENSMLUT00000002907.2; ENSMLUP00000002642.2; ENSMLUG00000002905.2.
DR GeneID; 102420854; -.
DR KEGG; mlf:102420854; -.
DR CTD; 51573; -.
DR eggNOG; KOG2258; Eukaryota.
DR GeneTree; ENSGT00510000047820; -.
DR HOGENOM; CLU_030006_2_1_1; -.
DR InParanoid; G1NYY0; -.
DR OMA; KHHWMTL; -.
DR OrthoDB; 2876171at2759; -.
DR TreeFam; TF313692; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:Ensembl.
DR GO; GO:0047395; F:glycerophosphoinositol glycerophosphodiesterase activity; IEA:Ensembl.
DR GO; GO:0004622; F:lysophospholipase activity; IEA:Ensembl.
DR GO; GO:0006580; P:ethanolamine metabolic process; IEA:Ensembl.
DR GO; GO:0070291; P:N-acylethanolamine metabolic process; IEA:Ensembl.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR CDD; cd08573; GDPD_GDE1; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR46320; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR PANTHER; PTHR46320:SF1; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 65..331
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 331 AA; 37674 MW; 145A63DD365857C3 CRC64;
MWLWETQGGL LGPFSFLLLL FLLVTRSPCN ACLFTGILYL LLRLFSFEPL PARRALQVLQ
PRDRVSAIAH RGGCHDAPEN TLAAIRQAAK NGATGVELDI EFTSDGVPVL MHDNTVDRTT
DGTGRICDLT FEQIRKLNPA ANHRLRNDFP NEKIPTLREG VVESLNQNLT IFFDVKGHAN
KAIDALKKIY MEFPQLYNTS MVCSFLPEVI YKMRQTDRNV VTALTHRPWS LSHTGDGKPR
YDNMWKLSTF VVLDILLDWS MHNVLWYLCG ISAFLVQKDS ISPNYLKKWS AKGIQVVGWT
VNTFDEKSYY ESYLGSSYIT DSMLEDCPPH Y
//
