ID G1P147_MYOLU Unreviewed; 343 AA.
AC G1P147;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Cilia- and flagella-associated protein 36 {ECO:0000256|ARBA:ARBA00021815};
DE AltName: Full=Coiled-coil domain-containing protein 104 {ECO:0000256|ARBA:ARBA00031593};
GN Name=CFAP36 {ECO:0000313|Ensembl:ENSMLUP00000003522.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000003522.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000003522.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000003522.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CFAP36 family.
CC {ECO:0000256|ARBA:ARBA00007460}.
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DR EMBL; AAPE02005064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006083387.1; XM_006083325.2.
DR AlphaFoldDB; G1P147; -.
DR STRING; 59463.ENSMLUP00000003522; -.
DR Ensembl; ENSMLUT00000003866.2; ENSMLUP00000003522.2; ENSMLUG00000003869.2.
DR GeneID; 102442726; -.
DR KEGG; mlf:102442726; -.
DR CTD; 112942; -.
DR eggNOG; KOG4511; Eukaryota.
DR GeneTree; ENSGT00390000012785; -.
DR HOGENOM; CLU_050059_0_0_1; -.
DR InParanoid; G1P147; -.
DR OMA; QILAMDD; -.
DR OrthoDB; 180864at2759; -.
DR TreeFam; TF315143; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0097546; C:ciliary base; IEA:Ensembl.
DR GO; GO:0035869; C:ciliary transition zone; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1520.10; ADP-ribosylation factor-like 2-binding protein, domain; 1.
DR InterPro; IPR023379; BART_dom.
DR InterPro; IPR042541; BART_sf.
DR InterPro; IPR038888; CFAP36.
DR PANTHER; PTHR21532:SF0; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36; 1.
DR PANTHER; PTHR21532; PHOSPHODIESTERASE HL; 1.
DR Pfam; PF11527; ARL2_Bind_BART; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 10..121
FT /note="BART"
FT /evidence="ECO:0000259|Pfam:PF11527"
FT REGION 165..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 39275 MW; 714EF4B3DC3526D1 CRC64;
MAAEEEDEVE WVVESIAGFL RGPDWSIPIL DFVEQKCEVF DDEEESKLTY TEIHQEYKEL
VEKLLEGYLK EIGINEDQFQ EACTSPLAKT RTSQAILQPV LAAEDFTIFK AMMVQKNIEM
QLQAIRIIQE RNGVLPDCLT DGSDVVSDLE QEEMKILREV LRKSKEEYDQ EEERKRKKQL
SEAKTEESTA NADETAKMSN SQGDGERDAH PPLEAKVHFA NSSVEPLAGK LEMLPETSSL
PQKGLKIPGF EYASTEGPIA NLSTLGTEEL RQREHYLKQK RDKLMSMRKD MKTKQMQNTE
QKGKPAGEVE EMTEKPEMTA EEMQTLLKRR LLAEKLKEEV INK
//
