ID G1P1P4_MYOLU Unreviewed; 612 AA.
AC G1P1P4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=RUN domain containing 1 {ECO:0000313|Ensembl:ENSMLUP00000003746.2};
GN Name=RUNDC1 {ECO:0000313|Ensembl:ENSMLUP00000003746.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000003746.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000003746.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000003746.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02024550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P1P4; -.
DR STRING; 59463.ENSMLUP00000003746; -.
DR Ensembl; ENSMLUT00000004112.2; ENSMLUP00000003746.2; ENSMLUG00000004114.2.
DR eggNOG; KOG3759; Eukaryota.
DR GeneTree; ENSGT00390000007311; -.
DR HOGENOM; CLU_020366_0_0_1; -.
DR InParanoid; G1P1P4; -.
DR OMA; WSYVART; -.
DR TreeFam; TF105949; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR CDD; cd17683; RUN_RUNDC1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR PANTHER; PTHR47194:SF5; RUN DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR47194; SORTING NEXIN-29-RELATED; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 420..601
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 17..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 67789 MW; AF213D797DE0414C CRC64;
MAAVEVAAEP VTVVAAVGPK AKDEEEEEEE SLPPCEAVRW APVGAVAEAG PGATAFSEEA
AAEDPGAAPG SPPDSPGRTL RRLRAERRRL DSALLALSSH FAQVRFRLRR VRGAPAEQQR
LLRELEDFAF RGCPHVLGYG EPGDPACDES DGLPGDRPRL RGEDQSEQEK RERLETQREK
QKELILQLKT QLDDLETFAY QEGNYDSLPQ SVVLERQRVI IDELIKKLDM NLNEDISSLS
TEELRQRVDA AVAQIVNPAR VKEQLVEQLK TQIRDLEMFI NFIQDEVGNP LQTDNGHCEC
KASGKTGNGS TRTGSSKLPP RNSKPKAEDV KKVRETGLHL MRRALAVLQI FAVSQFGCAT
GHIPQTLWPT GQADRDYSPL LKRLEVSVDR VKQLALRQQP YGHVITSANL QDLCQGGKDE
LTTAVRKELT VAMRDLLAHG LYASSPGMSL VMAPIACLLP AFSSAPEAMH PWELFVKYYH
AKNGRAYVES PARKLSQSFA LPVMGGTAMT PKQSLLTAIH MVLTEHDPFK RSADSELKAL
VCMALNEQRL VSWVNLICKS ASLIERHYQP WSYMAHTGFE SALNLLSRLS SLKFSLPVDL
AVRQLKNIKD AF
//
