ID G1P3D7_MYOLU Unreviewed; 357 AA.
AC G1P3D7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Ring finger protein 32 {ECO:0000313|Ensembl:ENSMLUP00000004425.2};
GN Name=RNF32 {ECO:0000313|Ensembl:ENSMLUP00000004425.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000004425.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000004425.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000004425.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02047031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02047032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006103274.1; XM_006103212.2.
DR AlphaFoldDB; G1P3D7; -.
DR STRING; 59463.ENSMLUP00000004425; -.
DR Ensembl; ENSMLUT00000004858.2; ENSMLUP00000004425.2; ENSMLUG00000004863.2.
DR GeneID; 102424462; -.
DR KEGG; mlf:102424462; -.
DR CTD; 140545; -.
DR eggNOG; KOG0800; Eukaryota.
DR GeneTree; ENSGT00390000003759; -.
DR HOGENOM; CLU_064517_0_0_1; -.
DR InParanoid; G1P3D7; -.
DR OMA; PQENDWD; -.
DR OrthoDB; 901745at2759; -.
DR TreeFam; TF329796; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0016235; C:aggresome; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005768; C:endosome; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16677; RING-H2_RNF32_rpt1; 1.
DR CDD; cd16678; RING-H2_RNF32_rpt2; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR042862; RNF32.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14991; RING FINGER PROTEIN 32; 1.
DR PANTHER; PTHR14991:SF0; RING FINGER PROTEIN 32; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF17123; zf-RING_11; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS50089; ZF_RING_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 129..171
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 295..347
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 37..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..62
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 40998 MW; 995EF6015234C532 CRC64;
MLKNKGHSSK RDNLAVTAVA LQDHILHDLQ LRNLSVADHS KTKVPKRENT SKSLKRNTKA
VKDTGLQKTV QGPEEEDPEK EYVLDPKPPP LTLAQKLGLF EPPLLPLSSD EWEQVKQRSI
SQGDSSQPCP ICREEFQLQP QVLLSCSHVF HRACLQAFEK FTSKKTCPLC RKSQYQTRVI
YDAARLFKAK CAIRIQACWR GHVVRKWYQD LRRTMPPTDT KLRRKFFEEK FTEISRRMLC
SYHTDIDELF AEIDHCLAIN RSVLQQLDGQ CGRRLTDDDW QEIQAQALQR EASECSICLA
PLAGSGRRPR EAVLLSCSHM FHHVCLLALE QFSWGDSSPF HACPLCRACY QKKILQS
//
