ID G1P4H9_MYOLU Unreviewed; 391 AA.
AC G1P4H9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000004865.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000004865.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000004865.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the KCTD3 family.
CC {ECO:0000256|ARBA:ARBA00009572}.
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DR EMBL; AAPE02069051; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P4H9; -.
DR STRING; 59463.ENSMLUP00000004865; -.
DR Ensembl; ENSMLUT00000005332.2; ENSMLUP00000004865.2; ENSMLUG00000005326.2.
DR eggNOG; KOG2714; Eukaryota.
DR GeneTree; ENSGT00940000153881; -.
DR HOGENOM; CLU_058696_0_0_1; -.
DR InParanoid; G1P4H9; -.
DR OMA; XPFGERD; -.
DR TreeFam; TF313754; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18393; BTB_POZ_SHKBP1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR047876; SHKBP1/KCTD3.
DR InterPro; IPR047825; SHKBP1_KCTD3_BTB_POZ.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15859; SETA BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15859:SF5; SH3KBP1-BINDING PROTEIN 1; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 19..88
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 147..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 42586 MW; 1D9940F634F4CCE5 CRC64;
MAAAAPAAEG FPGRGPPGEV IHLNVGGKRF STSRQTLTWI PDSFFSSLLS GRISTLKDET
GAIFIDRDPT VFAPILNFLR TKELDPRGVH GSSLLHEAQF YGLTPLVRRL QLREELDRSS
CGNVLFNGYL PPPAIVFPMK RRNRHSLVGP QQAGGRPAPV RRSNTMPPNL GNAGLLGRML
DEKAPPSPSG LPEEPGMVRL VCGHHNWIAV AYTQFLVCYR LKEASGWQLV FSSPRLDWPI
ERLALTARVL GGALGEHDKM VAAATGSEIL LWALQAEGGG SEIGVFHLGV PVEALFFVGN
QLIATSHTGR IGVWNAVTKH WQVQEVQPIT SYDAAGSFLL LGCSNGSIYY VDVQKFPLRM
KDNDLLVSEL YRDPAEDGVT ALSVYLTPKT S
//
