ID G1P5M9_MYOLU Unreviewed; 649 AA.
AC G1P5M9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=RAN binding protein 10 {ECO:0000313|Ensembl:ENSMLUP00000005328.2};
GN Name=RANBP10 {ECO:0000313|Ensembl:ENSMLUP00000005328.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000005328.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000005328.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000005328.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RANBP9/10 family.
CC {ECO:0000256|ARBA:ARBA00006535}.
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DR EMBL; AAPE02038704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P5M9; -.
DR STRING; 59463.ENSMLUP00000005328; -.
DR Ensembl; ENSMLUT00000005831.2; ENSMLUP00000005328.2; ENSMLUG00000005821.2.
DR eggNOG; KOG1477; Eukaryota.
DR GeneTree; ENSGT00940000158257; -.
DR HOGENOM; CLU_009129_4_0_1; -.
DR InParanoid; G1P5M9; -.
DR OMA; HIHSTGA; -.
DR TreeFam; TF331658; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:Ensembl.
DR CDD; cd12909; SPRY_RanBP9_10; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035782; SPRY_RanBP9/10.
DR PANTHER; PTHR12864; RAN BINDING PROTEIN 9-RELATED; 1.
DR PANTHER; PTHR12864:SF19; RAN-BINDING PROTEIN 10; 1.
DR Pfam; PF10607; CTLH; 2.
DR Pfam; PF08513; LisH; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00757; CRA; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 63..250
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 319..376
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT REGION 27..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 70132 MW; D0DB86CDF1B7388C CRC64;
RLAGHWLSGA DLVPLLPASS DTIAAPSKMA AATADRGAGS PQAGDSSGGG AGGGLPSPGE
QELSRRLQRL YPAVNQHETP LPRSWSPKDK YNYIGLSQGN LRVHYKGHGK NHKDAASVRA
THPIPAACGI YYFEVKIVSK GRDGYMGIGL SAQGVNMNRL PGWDKHSYGY HGDDGHSFCS
SGTGQPYGPT FTTGDVIGCC VNLINSTCFY TKNGHSLGIA FTDLPANLYP TVGLQTPGEI
VDANFGQQPF LFDIEDYMRE WRAKVQGTVH CFPISARLGE WQAVLQNMVS SYLVHHGYCA
TATAFARMTE TPIQEEQASI KNRQKIQKLV LEGRVGEAIE TTQRFYPGLL EHNPNLLFML
KCRQFVEMVN GTDSEVRSLS SRSPKSQDSY PGSPSLSPRH GPSSSHMHNT GADSPSCSNG
IASSKSKQNH SKYPAPSSSS SSSASSSSSS SPSSVNYSES NSTDSTKSQP HSSTSNQETS
DSEMEMEAEH YPNGVLESMS TRIVNGAYKH EDLQTDESSM DDGHPRRQLC GGNQAATERI
ILFGRELQAL SEQLGREYGK NLAHTEMLQD AFSLLAYSDP WSCPVGQQLD PIQREPVCAA
LNSAILESQN LPKQPPLMLA LGQASECLRL MARAGLGSCS FARVDDYLH
//
