ID G1P8J0_MYOLU Unreviewed; 333 AA.
AC G1P8J0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Cysteine and histidine-rich domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034547};
DE AltName: Full=CHORD domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034558};
GN Name=CHORDC1 {ECO:0000313|Ensembl:ENSMLUP00000006497.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000006497.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000006497.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000006497.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02025337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02025338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02025339; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P8J0; -.
DR STRING; 59463.ENSMLUP00000006497; -.
DR Ensembl; ENSMLUT00000007118.2; ENSMLUP00000006497.2; ENSMLUG00000007119.2.
DR eggNOG; KOG1667; Eukaryota.
DR GeneTree; ENSGT00940000154174; -.
DR HOGENOM; CLU_040079_0_0_1; -.
DR InParanoid; G1P8J0; -.
DR OMA; KGYTCCK; -.
DR TreeFam; TF105394; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06488; p23_melusin_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 2.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR039790; CHRD1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR12621; CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12621:SF9; CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF04968; CHORD; 2.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51401; CHORD; 2.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..64
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 158..217
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 228..317
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
SQ SEQUENCE 333 AA; 37521 MW; AE686D30B2296228 CRC64;
MPSMCYNRGC GQRFHAESNS DDACTYHPGV PVFHDALKGW TCCKRRTTDF SDFLSIVGCT
KGRHNNEKPP EPVKPEVKTT EKKELSELKP KFQEHIIQAP KPVEAIKRPS PDEPMTNLEL
KVSASLKQAL DKLKLSSGNE KNKVSEEDSD EIKIGTSCKN GGCTKTYQGL QSLEEVCVYH
SGVPIFHEGM KYWSCCRRKT SDFNTFLAQE GCTTGKHMWT AKDAGKKVVP CRHDWHQTGG
QVTISVYAKN SLPELSQVVA NSTLLNVHIV FEGEKEFHQN VKLWGVIDVK RSYVTMTATK
IEITMRKAEP MQWASLELPA AKNQEKQKEK KTE
//
