ID G1PRS3_MYOLU Unreviewed; 473 AA.
AC G1PRS3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Calcium binding tyrosine phosphorylation regulated {ECO:0000313|Ensembl:ENSMLUP00000013852.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000013852.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000013852.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000013852.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02049802; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PRS3; -.
DR STRING; 59463.ENSMLUP00000013852; -.
DR Ensembl; ENSMLUT00000015206.2; ENSMLUP00000013852.2; ENSMLUG00000015202.2.
DR eggNOG; ENOG502S1NF; Eukaryota.
DR GeneTree; ENSGT00390000000444; -.
DR HOGENOM; CLU_025626_0_0_1; -.
DR InParanoid; G1PRS3; -.
DR OMA; MCKNPVE; -.
DR TreeFam; TF332959; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048240; P:sperm capacitation; IEA:InterPro.
DR CDD; cd12100; DD_CABYR_SP17; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR InterPro; IPR038848; CABYR.
DR InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR InterPro; IPR047579; DD_CABYR_SP17.
DR PANTHER; PTHR15494; CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN; 1.
DR PANTHER; PTHR15494:SF0; CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN; 1.
DR Pfam; PF02197; RIIa; 1.
DR SMART; SM00394; RIIa; 1.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 12..49
FT /note="RIIa"
FT /evidence="ECO:0000259|SMART:SM00394"
FT REGION 79..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..165
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 50716 MW; E2C2BF883F498B10 CRC64;
MFSTKPRLVV PYGLKTLLEG VSRAVLKTNP PNITQFAAFY FKELIVFREG NIPLDIKDLV
RQFHQIKFEK WCEERTEEKK PEFIKEPEEA AAVPKEPTRV EKSTDTEEDH IFGPQFIHKT
TQFPSVYAEQ QPAPEDTSKA VRPPKPSTPK TTPTSSPSPV DIPPEFAYVP ADPAQFAAQM
LGNVSSTHSD QSEVLMVDVA TSLPVFSNEV LTSEVAEDTV VTTSVANSGE RVAVQVASHS
SVHVALGSKP TDDQAEPATA PSPSLQDEQD LPAFDQAPRG SWQAGTGGKA TPHISSIFND
KPVIEAVTHM ERTSEEVVIA FSDHIVSLKE IEQSPPESAI LIEKRVSGGP EKAEGSAALA
PLEDANHPSV QVEAEATILI SDTSLKGLLA QSLNPEGAAQ AIGSQRSLHL EVEIIALVPG
QEEDLAPPEA EEEDSVPPEA EVRPVGSGEA AEALHSGASV TPEIEPEGEA APA
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