ID G1PTD5_MYOLU Unreviewed; 1083 AA.
AC G1PTD5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Transcription elongation regulator 1 {ECO:0000313|Ensembl:ENSMLUP00000014484.2};
GN Name=TCERG1 {ECO:0000313|Ensembl:ENSMLUP00000014484.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000014484.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000014484.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000014484.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02012793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PTD5; -.
DR STRING; 59463.ENSMLUP00000014484; -.
DR Ensembl; ENSMLUT00000015902.2; ENSMLUP00000014484.2; ENSMLUG00000015879.2.
DR eggNOG; KOG0155; Eukaryota.
DR GeneTree; ENSGT00940000157770; -.
DR HOGENOM; CLU_008684_0_0_1; -.
DR InParanoid; G1PTD5; -.
DR OMA; KTRGEKX; -.
DR TreeFam; TF317748; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0070064; F:proline-rich region binding; IEA:Ensembl.
DR GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR CDD; cd00201; WW; 3.
DR Gene3D; 2.20.70.10; -; 3.
DR Gene3D; 1.10.10.440; FF domain; 6.
DR InterPro; IPR002713; FF_domain.
DR InterPro; IPR036517; FF_domain_sf.
DR InterPro; IPR045148; TCRG1-like.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR15377; TRANSCRIPTION ELONGATION REGULATOR 1; 1.
DR PANTHER; PTHR15377:SF7; TRANSCRIPTION ELONGATION REGULATOR 1; 1.
DR Pfam; PF01846; FF; 6.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00441; FF; 6.
DR SMART; SM00456; WW; 3.
DR SUPFAM; SSF81698; FF domain; 5.
DR SUPFAM; SSF51045; WW domain; 3.
DR PROSITE; PS51676; FF; 6.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 112..145
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 414..447
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 517..546
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 644..697
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 710..764
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 776..831
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 881..937
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 939..995
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 997..1062
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1061..1083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 696..723
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 17..84
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..329
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 122264 MW; 41BC0370AEF18FEE CRC64;
RMAQQQALRF RGPAPPPNAV MRGPPPLMRP PPPFGMMRGP PPPPRPPFGR PPFDPNMPPM
PPPGGIPPPM GPPHLQRPPF MPPPMGTMPP PPGMMFPPGM PPVSAPGTPA LPPTEEIWVE
NKTPDGKVYY YNARTRESAW SKPDGVKVIQ QSELTPMLAA QAQVQAQAQA QAQAQAQAQA
QAQAQAQAQA QAQAQAQAQA QAQAQAQAQA QAQAQAQAQA QAQAQAQAQA QAQAQVQAQA
VGASTPTTSS PAPAVSTSTS SSTPSSTTST TTTASSVSQT VSTPTTQDQT PSSAVSVATP
TVSVSTPAPT ATPVQNVPQP HPQTLPPAVP HSVPQPAAAI PAFPPVMVPP FRVPLPGMPI
PLPGVAMMQI VSCPYVKTVA TTKTGVLPGM APPIVPMIHP QVAIAASPAT LAGATAVSEW
TEYKTADGKT YYYNNRTLES TWEKPQELKE KEKLEEKIKE PIKEPSEEPL PMETEEEDPK
EEPIKEIKEE PKEEEMTEEE KAAQKAKPVA TTPIPGTPWC VVWTGDERVF FYNPTTRLSM
WDRPDDLIGR ADVDKIIQEP PHKRGMEELR KLRHPTPTML SIQKWQFSMS AIKEEQELME
ELNEDEPVKA KKRKRDDNKD IDSDKEAAME AEIKAARERA IVPLEARMKQ FKDMLLERGV
SAFSTWEKEL HKIVFDPRYL LLNPKERKQV FDQYVKTRAE EERREKKNKI MQAKEDFKKM
MEEAKFNPRA TFSEFAAKHA KDSRFKAIEK MKDREALFNE FVAAARKKEK EDSKTRGEKI
RSDFFELLSN HHLDSQSRWS KVKDKVESDP RYKAVDSSSM REDLFKQYIE KIAKNLDSEK
EKELERQARI EASLRERERE VQKARSEQTK EIDREREQHK REEAIQNFKA LLSDMVRSSD
VSWSDTRRTL RKDHRWESGS LLEREEKEKL FNEHIEALTK KKREHFRQLL DETSAITLTS
TWKEVKKIIK EDPRCIKFSS SDRKKQREFE EYIRDKYITA KADFRTLLKE TKFITYRSKK
LIQESDQHLK DVEKILQNDK RYLVLDCVPE ERRKLIVAYV DDLDRRGPPP PPTASEPTRR
STK
//
