ID G1PVT6_MYOLU Unreviewed; 1002 AA.
AC G1PVT6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Ankyrin repeat domain 35 {ECO:0000313|Ensembl:ENSMLUP00000015471.2};
GN Name=ANKRD35 {ECO:0000313|Ensembl:ENSMLUP00000015471.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000015471.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000015471.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000015471.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAPE02033317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PVT6; -.
DR STRING; 59463.ENSMLUP00000015471; -.
DR Ensembl; ENSMLUT00000016972.2; ENSMLUP00000015471.2; ENSMLUG00000016966.2.
DR eggNOG; ENOG502QXWS; Eukaryota.
DR GeneTree; ENSGT00530000063074; -.
DR HOGENOM; CLU_298955_0_0_1; -.
DR InParanoid; G1PVT6; -.
DR OMA; HGANEDC; -.
DR TreeFam; TF331274; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24161; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24161:SF117; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 5.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 53..85
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 86..118
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 119..151
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 152..184
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 185..217
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 249..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 293..320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 625..652
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 917..958
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 458..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 108576 MW; 2279E52897254FBC CRC64;
MKRFFSCSSS QVAVERWNRR DQKLLEAVQR GDVGRVAALA SRKSSRPTKL DANGQSPFHL
AASKGLTECL TILLANGADI NSKNEDGSTA LHLATISCQP QCVKVLLQHG ANEDAVDAEN
RSPLHWAASS GCASSVLLLC DHEAFLDVLD NDGRTPLMIA SLGGHAAICS QLLQRGARVN
VTDKDDKSAL ILACEKGSAE VAELLLSHGA DAGAVDSAGH DALYYGLRTQ DKALWKLLQQ
ALSWRRGGQG LVQHPDAASK ASPSEPPVGS QPKSPRGAEP GAEQEKEREE VCSEEWRWKY
EEEQKKVSQL EQELVGKTEE SKAQAAAYLG LANQIREQVQ ELGRLLFREP RAPGGQSPGI
RPGGDGMEQG CPLDLLAEGI RELKKQQQAV AAAAANPVLA SKKTEDSSPR EMCYEAHARS
QPEQGPPQGP VSEIPGEAAG QHQTTVGGQA LGPERAAQPH AGRKERRKAP GAERAGTAAG
AAGTAAMNQL LLQLREELAA VWREKDAALG ALSRPVLEGV LGKSRAEATA AAWEKMEARL
EQVLLKLDRA KAGLRATPAT PAQESREGAP KAGSETIPEE DGEKETGAPG TQRESPGAPG
RPQTPGGGLA KGMLEKEVSA LRLSNSNLLE ELGELGRERQ RLQGELQSLS QRLQREFVPR
PVAQVQLQQL RWSVGLLTDE LAVEKEATEK LRRHLASQSS GLRGLWDCLP PDLVGKAGAR
GPGPEPLQEL QACISALVAR HREAQQMLAR LEEENQRLRG ASAPHPEPGP SSQATAPPEV
AALEQDLGQL EEELRAVQAS MRGKSQEIGK LKQLLYQATE EVAELRAREA ASLRQHERAR
SSLAAQAQAW SQELKALLEK YNSACCEVGR LQEAVADERC RSGDLAARAT EQERQASEMR
GRSEQFEKTV GLLREKMEHL LGACQDKEAK IKELLKKVEQ LSEEVLAVRG ENARLASQLR
DSQKNHEEII STYRNHLLSA AQGYMEQDVY NILLRILSRQ EK
//
