ID G1Q3G2_MYOLU Unreviewed; 466 AA.
AC G1Q3G2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Tripartite motif containing 75, pseudogene {ECO:0008006|Google:ProtNLM};
GN Name=LOC102430530 {ECO:0000313|Ensembl:ENSMLUP00000018245.1};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000018245.1, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000018245.1, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000018245.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02026513; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006093533.1; XM_006093471.2.
DR AlphaFoldDB; G1Q3G2; -.
DR STRING; 59463.ENSMLUP00000018245; -.
DR Ensembl; ENSMLUT00000026027.1; ENSMLUP00000018245.1; ENSMLUG00000022628.1.
DR GeneID; 102430530; -.
DR KEGG; mlf:102430530; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000162839; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; G1Q3G2; -.
DR OMA; IWAEANC; -.
DR OrthoDB; 5192320at2759; -.
DR TreeFam; TF338674; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16607; RING-HC_TRIM60-like_C-IV; 1.
DR CDD; cd15829; SPRY_PRY_TRIM75; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035785; SPRY/PRY_TRIM75.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF690; TRIPARTITE MOTIF-CONTAINING PROTEIN 75; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 92..133
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 275..466
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 466 AA; 53605 MW; 3B6E1BA654208A54 CRC64;
MAGEGAVAKL QTEINCPICL DNLRDPVTIE CGHNFCRSCI ERSWADVQDR FPCPVCRHPC
KERHLWSNTQ LGRMVDMVKL LQITGAKVKQ QEERRLCEKH NQALTLFCEE DLKLLCPLCT
QPPDHQGHHV RPVEEAASHH RQKLRSYIEP LKLADLQKLL ATQDRQRSEL REKVEKRRAK
LASEYESVIA SIECEQAEVH SRLAAQEKHI LRNLTANKAA FSDHISKLRV LRKEMAEMSV
VSDVKLLMNI KGVLHRCDNL EPPDVYCVKY KREEFSLPPQ CSALLQIMQT FREEVTLDPE
TAHPNLLVSE DKKSVTFVRK KQGVHWNPKG FADDTVVLGS EGFDCGRHYW EVQVDDKPEW
AVGVCTDSLS KERKQPLLRQ ENRCWTIQLQ DGDYVARGPV PVTLVLQEMP RGIGIYLDYE
MGHVSFYSLN DMSHIHSFRD TFSEVLKPYF YVGCDPKPLT IRALKD
//
