ID G1QH47_NOMLE Unreviewed; 553 AA.
AC G1QH47;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=SH3 domain binding protein 2 {ECO:0000313|Ensembl:ENSNLEP00000000230.3};
GN Name=SH3BP2 {ECO:0000313|Ensembl:ENSNLEP00000000230.3};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000000230.3, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000000230.3, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000000230.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01116166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116171; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01116173; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QH47; -.
DR Ensembl; ENSNLET00000000247.3; ENSNLEP00000000230.3; ENSNLEG00000000199.3.
DR eggNOG; ENOG502RF2Z; Eukaryota.
DR GeneTree; ENSGT00390000002216; -.
DR HOGENOM; CLU_040124_0_0_1; -.
DR InParanoid; G1QH47; -.
DR OMA; RNYRIFQ; -.
DR TreeFam; TF333342; -.
DR Proteomes; UP000001073; Chromosome 20.
DR GO; GO:0001784; F:phosphotyrosine residue binding; IEA:Ensembl.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd13308; PH_3BP2; 1.
DR CDD; cd10359; SH2_SH3BP2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035848; SH3BP2.
DR InterPro; IPR035847; SH3BP2_SH2.
DR PANTHER; PTHR15126:SF4; SH3 DOMAIN-BINDING PROTEIN 2; 1.
DR PANTHER; PTHR15126; SH3-BINDING; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 54..158
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 449..547
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 195..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 553 AA; 60965 MW; 327B46A3863A0F3F CRC64;
ARVRRDGTWA GPQSRGSRAR CGFPTKLFMA AEEMHWPVPM KPIGAQNLLT MPGGVAKAGF
LHKKGGTQLQ LLKWPLRFVI IHKRCVYYFK SSTSASPQGA FSLSGYNRVM RAAEETTSNN
VFPFKIIHIS KKHRTWFFSA SSEDERKSWM ALLRREIGHF HEKKDLPLDT SVGPVSVRVQ
PGSLCSADAL MHPPAYPPPP VPTPRKPAFS DMPRAHSFTS KGPGPLLPPP PPKHGLPDVG
LAAEDSKRDP LCPRRAEPCP RVPATPRRMS DPPPGTMPTA PSLRKPPCFR ESASPSPEPW
IPGHGACSTS SAAIMAAVTS RNCDKLKSFH LSPRGPPTSE PPPVPANKPK FLKTAEEDPP
REAAMPGLFV PPVAPRPPAL KLPVPEATAR PAVLPRPEKP QLPHLQRSPP DGQSFRSFSF
EKPRQPSQAD AGGDDSDEDY EKVPLPNSVF INTTESCEVE RLFKATSPRG EPQDGLYCIR
NSSTKSGKVL VVWDETSNKV RNYRIFEKDS KFYLEGEVLF VSVGSMVEHY HTHVLPSHQS
LLLRHPYGYS GPR
//
