ID G1QMZ8_NOMLE Unreviewed; 405 AA.
AC G1QMZ8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=RNF130 {ECO:0000313|Ensembl:ENSNLEP00000002314.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000002314.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000002314.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000002314.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01119017; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119021; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01119025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012360533.1; XM_012505079.1.
DR AlphaFoldDB; G1QMZ8; -.
DR Ensembl; ENSNLET00000002440.2; ENSNLEP00000002314.2; ENSNLEG00000001941.2.
DR eggNOG; KOG0800; Eukaryota.
DR GeneTree; ENSGT00940000157465; -.
DR HOGENOM; CLU_049885_2_0_1; -.
DR TreeFam; TF317486; -.
DR Proteomes; UP000001073; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16803; RING-H2_RNF130; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46539; E3 UBIQUITIN-PROTEIN LIGASE ATL42; 1.
DR PANTHER; PTHR46539:SF27; RING FINGER PROTEIN 130; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..405
FT /note="RING-type domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014165967"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 250..291
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 405 AA; 44929 MW; 393619EF3D06BB8F CRC64;
MSCAGRAGPA RLAALALLTC SLWYINVTVQ EPGRGAPLTF RIDRGRYGLN SPKAEVRGQV
LAPLPLHGVA DHLGCDPQTR FFVPPNIKQW IALLQRGNCT FKEKISRAAF HNAVAVVIYN
NKSKEEPVTM THPGTGDIIA VMITELRGKD ILSYLEKNIS VQMTIAVGTR MPPKNFSRGS
LVFVSISFIV LMIISSAWLI FYFIQKIRYT NARDRNQRRL GDAAKKAISK LTTRTVKKGD
KETDPDFDHC AVCIESYKQN DVVRILPCKH VFHKSCVDPW LSEHCTCPMC KLNILKALGI
VPNLPCTDNV AFDMERLTRT QAVNRRSALG DLAGDNTLGL EPLRTSGISP LPQDGELTPR
TGEINIAVTK EWFIIASFGL LSALTLCYMI IRATASLNAN EVEWF
//
