ID G1QN58_NOMLE Unreviewed; 404 AA.
AC G1QN58;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Kinesin light chain {ECO:0000256|RuleBase:RU367020};
GN Name=KLC3 {ECO:0000313|Ensembl:ENSNLEP00000002374.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000002374.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000002374.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000002374.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Kinesin is a microtubule-associated force-producing protein
CC that play a role in organelle transport.
CC {ECO:0000256|RuleBase:RU367020}.
CC -!- SUBUNIT: Oligomeric complex composed of two heavy chains and two light
CC chains. {ECO:0000256|RuleBase:RU367020}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367020}.
CC Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the kinesin light chain family.
CC {ECO:0000256|ARBA:ARBA00009622, ECO:0000256|RuleBase:RU367020}.
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DR EMBL; ADFV01101950; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01101951; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01101952; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01101953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QN58; -.
DR Ensembl; ENSNLET00000002503.2; ENSNLEP00000002374.2; ENSNLEG00000001990.2.
DR eggNOG; KOG1840; Eukaryota.
DR GeneTree; ENSGT00940000162356; -.
DR HOGENOM; CLU_019953_2_0_1; -.
DR TreeFam; TF314010; -.
DR Proteomes; UP000001073; Chromosome 17.
DR GO; GO:0005871; C:kinesin complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR002151; Kinesin_light.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45783; KINESIN LIGHT CHAIN; 1.
DR PANTHER; PTHR45783:SF1; KINESIN LIGHT CHAIN 3; 1.
DR Pfam; PF13424; TPR_12; 2.
DR PRINTS; PR00381; KINESINLIGHT.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|RuleBase:RU367020};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW ECO:0000256|RuleBase:RU367020};
KW Differentiation {ECO:0000256|ARBA:ARBA00022871};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU367020};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175,
KW ECO:0000256|RuleBase:RU367020};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 193..226
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 235..268
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 39..94
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 101..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 404 AA; 44669 MW; D575CB00D99AD901 CRC64;
MPPVPSWGSP GSGGLTGVEP TSTWDPHPGQ VLLALSAHVG ALEAEKQRLR SQARRLAQEN
VWLREELEET QRRLRASEEA VAQLEEEKRH LEFLGQLRQY DPPAENQQSE SPPRRDSLAS
LFPSEEEERK GPEAAGAAAA QQGGYEIPAR LRTLHNLVIQ YAGQGRYEVA VPLCRQALED
LERSSGHCHP DVATMLNILA LVYRDQNKYK EATDLLHDAL QIREQTLGPE HPAVAATLNN
LAVLYGKRGR YREAEPLCQR ALEIREKVLG ADHPDVAKQL NNLALLCQNQ GKFEDVERHY
ARALSIYEAL GGPHDPNVAK TKNNLASAYL KQNKYQQAEE LYKEILHKED LPAPLGAPNT
GTAGDAEQTL RRSSSLSKIR ESIRRGSEKL VSRLRGEGAA GAAG
//
