ID G1QZ06_NOMLE Unreviewed; 688 AA.
AC G1QZ06;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=G protein nucleolar 1 (putative) {ECO:0000313|Ensembl:ENSNLEP00000006177.2};
GN Name=GNL1 {ECO:0000313|Ensembl:ENSNLEP00000006177.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000006177.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000006177.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000006177.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01069197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01069198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01069199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01069200; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01069201; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QZ06; -.
DR STRING; 61853.ENSNLEP00000006177; -.
DR Ensembl; ENSNLET00000006493.2; ENSNLEP00000006177.2; ENSNLEG00000005058.2.
DR eggNOG; KOG1424; Eukaryota.
DR GeneTree; ENSGT00940000158047; -.
DR HOGENOM; CLU_013649_1_1_1; -.
DR InParanoid; G1QZ06; -.
DR OMA; CDFPVRP; -.
DR TreeFam; TF324569; -.
DR Proteomes; UP000001073; Chromosome 1a.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:Ensembl.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR043358; GNL1-like.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45709; LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45709:SF6; PROTEIN NUCLEOLAR 1 (PUTATIVE)-RELATED; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 363..393
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..567
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 78039 MW; C36EE9E55924333D CRC64;
MPRKKPFSVK QKKKQLQDKR ERKRGLQDGL RSSSNSRSGS RERREEQTDT SDGESVTHHI
RRLNQQPSQG LGPRGYDPNR YRLHFERDSR EEVERRKRAA REQVLQPVSA EVLELDIREV
YQPGSVLDFP RRPPWSYEMS KEQLMSQEER SFQEYLGKIH GAYSSEKLSY FEHNLETWRQ
LWRVLEMSDI VLLITDIRHP VVNFPPALYE YVTGELGLAL VLVLNKVDLA PPALVVAWKH
YFHQHYPQLH VVLFTSFPRD PRTPQDPSSV LKKSRRRGRG WTRALGPEQL LRACEAITVG
KVDLSSWREK IARDVAGATW GNGSGEEEEE EDGPAVLVEQ QTDSAMEPTG PTRERYKDGV
VTIGCVGFPN VGKSSLINGL VGRKVVSVSR NPGPYPILSD LLSYPFCLIF PSLLPRQLQV
LAGIYPIAQI QEPYTAVGYL ASRIPVQALL HLRHPEAEDP SAEHPWCAWD ICEAWAEKRG
YKTAKAARND VYRAANSLLR LAVDGRLSLC FHPPGYSEQK GQSTWESHPE TTELVVLQGR
VGPAGDEEEE EEEELSSSCE EEGEEDRDCS WTGCPLDGGV RSTRLLFALK QILSGSESLG
SFSNASRQTL LTKKQRKVYL KRLRCLATYS FRFISIGLSV DITPGIHSSA KFKYYQHENV
LEGFSKCARQ EKRSQLREKS TCLPSGAL
//
