ID G1R1S9_NOMLE Unreviewed; 772 AA.
AC G1R1S9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Tetratricopeptide repeat domain 14 {ECO:0000313|Ensembl:ENSNLEP00000007151.1};
GN Name=TTC14 {ECO:0000313|Ensembl:ENSNLEP00000007151.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000007151.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000007151.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000007151.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01170508; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003256564.1; XM_003256516.1.
DR AlphaFoldDB; G1R1S9; -.
DR STRING; 61853.ENSNLEP00000007151; -.
DR Ensembl; ENSNLET00000007506.2; ENSNLEP00000007151.1; ENSNLEG00000005900.2.
DR GeneID; 100595218; -.
DR KEGG; nle:100595218; -.
DR CTD; 151613; -.
DR eggNOG; ENOG502QPJ1; Eukaryota.
DR GeneTree; ENSGT00390000013701; -.
DR HOGENOM; CLU_020585_1_0_1; -.
DR InParanoid; G1R1S9; -.
DR OMA; IRKEEWY; -.
DR OrthoDB; 2918730at2759; -.
DR TreeFam; TF325777; -.
DR Proteomes; UP000001073; Chromosome 11.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd00164; S1_like; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR039190; TTC14.
DR PANTHER; PTHR23184; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR PANTHER; PTHR23184:SF9; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR Pfam; PF13414; TPR_11; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50126; S1; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 126..208
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REPEAT 307..340
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 341..374
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 36..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..515
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 88469 MW; 6F256A4E5212E5CA CRC64;
MDRDLLRQSL NCHGSSLLSL LRSEQQDNPH FRSLLGSAAE PARGPPPQQP LQGRKEKRVD
NIEIQKFISK KADLLFALSW KSDAPATSEI NEDSEDHYAV MPPLEQFMEI PSVDRRELFF
RDIERGDIVI GRISSIREFG FFMVLICLGS GIMRDITHLE ITALCPLRDV PSHSNHGDPL
SYYQTGDIIR AGIKDIDRYH EKLAVSLYSS SLPPHLSGIK LGVISSEELP LYYRRSVELT
SNSLESYENI MQSSLGFVNP GVVEFLLEKL GIDESNPPSL MRGLQSKNFS EDDFASALRK
KQSASWALKC VKIGVDYFKV GRHVDAMNEY NKALEIDKQN VEALVARGAL YATKGSLNKA
IEDFELALEN CPTHRNARKY LCQTLVERGG QLEEEEKFLN AESYYKKALA LDETFKDAED
ALQKLHKYMQ KSLELREKQA EKEEKQKTKK IETSAEKLRK LLKEEKRLKK KRRKSTSSSS
SSVSSADESV SSSSSSSSSG HKRHKKHKRN RSESSRSSRR HSSRASSNQI DENRKDECYP
VPANTSASFL NHKQEVEKLL GKQDRLQYEK TQIKEKDRCP LSSSSLEIPD DFGGRSEDPR
DFYNSYKTQA GSSKTEKPYK SERHFSSRRN SSDSFCRNSE DKIYGYRRFE KDIEGRKEYY
RRWEPGSVRH STSPASSDYS WKSVEKYKKY AHSGSRDFSR HEQRYRLNTN QGEYEREDNY
GEDIKTEVPE EDALSSKEHS ESSVKKNLPQ NLLNIFNQIA EFEKEKGNKS KT
//
