ID G1R5J4_NOMLE Unreviewed; 2002 AA.
AC G1R5J4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Ankyrin repeat domain 12 {ECO:0000313|Ensembl:ENSNLEP00000008466.3};
GN Name=ANKRD12 {ECO:0000313|Ensembl:ENSNLEP00000008466.3};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000008466.3, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000008466.3, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000008466.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01007825; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01007826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01007827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01007828; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 61853.ENSNLEP00000008466; -.
DR Ensembl; ENSNLET00000008867.3; ENSNLEP00000008466.3; ENSNLEG00000006948.3.
DR eggNOG; ENOG502QQG5; Eukaryota.
DR GeneTree; ENSGT00940000154742; -.
DR HOGENOM; CLU_001632_0_0_1; -.
DR InParanoid; G1R5J4; -.
DR OMA; PQVHHPR; -.
DR TreeFam; TF326440; -.
DR Proteomes; UP000001073; Chromosome 4.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24149; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12; 1.
DR PANTHER; PTHR24149:SF16; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT REPEAT 184..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 217..249
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 250..282
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1094..1249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1417..1439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1696..1728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..661
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..683
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..1075
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1160..1225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1703..1724
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2002 AA; 228894 MW; B508FCAA47D8B061 CRC64;
MPKSGFTKPV QSENSDSDSN MVEKPYGRKS KDKIASYSKT PKIERSDVSK EMKEKSSMKR
KLPFTISPSR NEERDSDTDS DPGHTSENWG ERLISSYRTY SEKEGPEKKK TKKEAGNKKS
TPVSILFGYP LSERKQMALL MQMTARDNSP DSTPNHPSQT TPAQKKTPSS SSRQKDKVNK
RNERGETPLH MAAIRGDVKQ VKELISLGAN VNVKDFAGWT PLHEACNVGY YDVAKILIAA
GADVNTQGLD DDTPLHDSAS SGHRDIVKLL LRHGGNPFQA NKHGERPVDV AETEELELLL
KREVPLSDDD ESYTDSEEAQ SVNPSSVDEN IDSETEKDSL ICESKQILPS KTPLPSALDE
YEFKDDDDEE INKMIDDRHI LRKEQRKENE PEAEKTHLFA KQEKAFYPKS FKSKKQKPSR
VLYSSTESSD EEALQNKKIS TSCSVIPETS NSDIQTKKEY VVSGEHKQKG KVKRKLKNQN
KNKENQELKQ EKEGKENTRI TNLTVNTGLD SSEKTREEGN FRKSFSPKDD TSLHLFHIST
GKSPKHSCGL SEKQSTPLKQ EHTKTCLSPG SSEMSLQPDL VRYDNTESEF LPESSSVKSC
KHKEKSKHQK DFHLEFGEKS NAKIKDEDHS PTFENSDCTL KKMDKEGKTL KKHKLKHKER
EKEKHKKEIE GEKEKYKTKD SAKELQRSVE FDREFWKENF FKSDETEDLF LNMEHESLTL
EKKSKLEKNI KDDKSTKEKH VSKERNFKEE RDKIKKESEK SFREEKIRDL KEERENIPTD
KDSEFTSLGM SAIEESIGLH LVEKEVDIEK QEKHIKESKE KPEKRSQTKE KDIEKMERKN
SEKEKKIKHE HKSEKDKLDL SECVDKIKEK DKLYSHHTEK CHKEGEKSKN TAAIKKTDDR
EKSREKMDRK HDKEKPEKER HLAESKEKHL MEKKNKQSDN SDYSKSEKGK NKEKDRELDK
KEKSRDKESI NITNYKHIQE EKKSSIVDGN KAQHDKPLSL KEKTKDEPLK TPDGKEKDKK
DKDIDRYKER DKHKDKIQLN SLLKLKSEAD KPKPKSSPAS KDTRPKEKRL VNDDLMQTSF
ERMLSLKDLE IEQWHKKHKE KIKQKEKERL RNRNCLELKI KDKEKIKHTP TESKNKELTR
SKSSEVTDAY TKEKQPKDAV SNRSQSVDTK NVMTLGKSSF VSDNSLNRSP RSENEKPGLS
SRSVSMISVA SSEDSCHTTV TTPRPPVEYD SDFMLESSES XXXXXXXXXX XXXXXXXXXX
XXXXXXXXXX XXXXXXTVPR DTSPSPKPEV FSNVPERDLS NVSNIHSSFA ASPTGASNSK
YVSADRNLIK NTAPVSTVMD SPVHLEPSSQ VGVIQNKSWE MPVDRLETLS TRDFICPNSN
IPDQESSLQS FCNSENKILK ENADFLSLHQ TELPGNSCAQ DPASLMPSQQ PCSFPSQSLS
DAESISKHMS LSYVANQEPG ILQQKNPVQI ISSALDTDNE STKDTENTFV LGDVQKTDAF
VPVYSDSTIQ EASPNFEKAY TLPVLSSEKD FNGSDTSTQL NTHYAFSKLT YKSSSGHEVE
NSTTDIQVIS HEKENKLESL VLTHLNRCDS DLCEMNAGMP KGNLNEQDPK HCPESEKCLL
SIEDEESQQS ILSSLENHSQ QSAQPEMHKY GQLVKVELEE NAEDDKTENQ IPQRMTRNKA
NTMANQSKQI LASCTLLSEK DSESSSPRGR IRLTEDDDPQ IHHPRKRKVS RVPQPVQVSP
SLLQAKEKAQ QSLAAIVDSL KLDEIQPYSS ERANPYFEYL HIRKKIEEKR KLLCSVIPQA
PQYYDEYVTF NGSYLLDGNP LSKICIPTIT PPPSLSDPLK ELFRQQEVVR MKLRLQHSIE
REKLIVSNEQ EVLRVHYRAA RTLANQTLPF SACTVLLDAE VYNVPLDSQS DDSKTSVRDR
FNARQFMSWL QDVDDKFDKL KTCLLMRQQH EAAALNAVQR LEWQLKLQEL DPATYKSISI
YEIQEFYVPL VDVNDDFELT PI
//
