ID G1R782_NOMLE Unreviewed; 327 AA.
AC G1R782;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=V-set and immunoglobulin domain containing 2 {ECO:0000313|Ensembl:ENSNLEP00000009054.1};
GN Name=VSIG2 {ECO:0000313|Ensembl:ENSNLEP00000009054.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000009054.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000009054.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000009054.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01057469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003253382.1; XM_003253334.1.
DR AlphaFoldDB; G1R782; -.
DR STRING; 61853.ENSNLEP00000009054; -.
DR Ensembl; ENSNLET00000009488.2; ENSNLEP00000009054.1; ENSNLEG00000007438.2.
DR GeneID; 100590886; -.
DR KEGG; nle:100590886; -.
DR CTD; 23584; -.
DR eggNOG; ENOG502RYI3; Eukaryota.
DR GeneTree; ENSGT00940000161544; -.
DR HOGENOM; CLU_040549_1_0_1; -.
DR InParanoid; G1R782; -.
DR OMA; CLIKFQK; -.
DR OrthoDB; 3024056at2759; -.
DR TreeFam; TF330875; -.
DR Proteomes; UP000001073; Chromosome 15.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR042475; VSIG2.
DR PANTHER; PTHR45046; V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR45046:SF1; V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..327
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003421014"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..125
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 144..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 273..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 34346 MW; C6A948457F950BDF CRC64;
MAELPGPFLC GALLGFLCLS GLAVEVKVPT EPLSTPLGKT AELTCTYSTS VGDSFALEWS
FVQPGKPISE SHPILYFTNG HLYPTGSKSK RVSLLQNPPT VGVATLKLTD VHPSDTGTYL
CQVNNPPDFY TNGLGLINLT VLVPPSNPLC SQSGQTSVGG STALRCSSSE GAPKPVYNWV
RLGTFPTPSP GSMVQDEVSG QLILTNLSLT SSGTYRCVAT NQMGSASCEL TLSVTEPSQG
RVAGALIGVL LGVLLLSVAA FCLIRFQKER GKKPKETYGG SDLREDAIAP GISEHTSMRA
DSSKGFLERP SSASTVTTTK SKLPMVV
//
