ID G1RJK7_NOMLE Unreviewed; 491 AA.
AC G1RJK7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 3.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Cytoplasmic polyadenylation element binding protein 1 {ECO:0000313|Ensembl:ENSNLEP00000013414.3};
GN Name=CPEB1 {ECO:0000313|Ensembl:ENSNLEP00000013414.3};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000013414.3, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000013414.3, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000013414.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR EMBL; ADFV01044197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044200; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044201; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01044203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003268507.1; XM_003268459.1.
DR AlphaFoldDB; G1RJK7; -.
DR Ensembl; ENSNLET00000014077.3; ENSNLEP00000013414.3; ENSNLEG00000011018.3.
DR GeneID; 100607024; -.
DR CTD; 64506; -.
DR eggNOG; KOG0129; Eukaryota.
DR GeneTree; ENSGT00940000155524; -.
DR HOGENOM; CLU_014948_1_1_1; -.
DR OMA; NCYGPLS; -.
DR OrthoDB; 2897681at2759; -.
DR TreeFam; TF317658; -.
DR Proteomes; UP000001073; Chromosome 6.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12723; RRM1_CPEB1; 1.
DR CDD; cd12725; RRM2_CPEB1; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032292; CEBP1_N.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR034977; CPEB1_RRM1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF9; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1; 1.
DR Pfam; PF16368; CEBP1_N; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 236..333
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 355..436
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 87..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 54176 MW; A90DB1D71F879CED CRC64;
MLFPTSAQES SRGLPDANDL CLGLQSLSLT GWDRPWSTQD SDSSAQSSTH SVLSMLHNPL
GNVLGKPPLS FLPLDPLGSD LVDKFPAPSV RGSRLDTRPI LDSRSSSPSD SDTSGFSSGS
DHLSDLISSL RISPPLPFLS LTGGGPRDPL KMGVGSRMDQ EQAALAAVTP SPTSASKRWP
GASVWPSWDL LEAPKDPFSI EREARLHRQA AAVNEATCTW SGQLPPRNYK NPIYSCKVFL
GGVPWDITEA GLVNTFRVFG SLSVEWPGKD GKHPRCPPKG NMPKGYVYLV FELEKSVRSL
LQACSHDPLS PDGLSEYYFK MSSRRMRCKE VQVIPWVLAD SNFVRSPSQR LDPSRTVFVG
ALHGMLNAEA LAAILNDLFG GVVYAGIDTD KHKYPIGSGR VTFNNQRSYL KAVSAAFVEI
KTTKFTKKVQ IDPYLEDSLC HICSSQPGPF FCRDQVCFKY FCRSCWHWRH SMEGLRHHSP
LMRNQKNRDS S
//
