ID G1RKJ4_NOMLE Unreviewed; 441 AA.
AC G1RKJ4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Tripartite motif containing 4 {ECO:0000313|Ensembl:ENSNLEP00000013751.2};
GN Name=TRIM4 {ECO:0000313|Ensembl:ENSNLEP00000013751.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000013751.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000013751.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000013751.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01105253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01105254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01105255; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1RKJ4; -.
DR STRING; 61853.ENSNLEP00000013751; -.
DR Ensembl; ENSNLET00000014429.2; ENSNLEP00000013751.2; ENSNLEG00000011309.3.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000163330; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; G1RKJ4; -.
DR OMA; VGVCQED; -.
DR TreeFam; TF338674; -.
DR Proteomes; UP000001073; Chromosome 17.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15809; SPRY_PRY_TRIM4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR035829; PRY/SPRY_TRIM4.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF670; E3 UBIQUITIN-PROTEIN LIGASE TRIM4; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 12..53
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 229..441
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 159..190
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 441 AA; 50722 MW; 737BE920714014F4 CRC64;
MEAEDLQEEL TCAICLDYFQ DPVSIECGHN FCRGCLHRSW APGGGPFPCP ECRHPSAPPH
PLPLLMWSPA ELICSNFDIH MDEWKRRLIR LLFYHFKQEK LLKSQRVFVA KMKKVMRLQD
VEVKNATQWK DKIKSQRMRI STEFSKLHNF LVEEEDLFLQ RLNKEEEETK KKLNENTLKL
NQTIASLKRL ILEVGEKSQA PTLELLQSSL LYLLRSEIQD MNYSLEAVKV KTVCQIPLMK
EMLKRFQVAV NLAEDTAHPK LVFSQEGRYV KNTASASSWP VFSSAWNYFA GWRNPQKTAY
AERFQHLPCV LGKNAFTSGK HYWEVESRDS LEVAVGVCRE DVMGITDRSK MSPDVGIWAI
YWSAAGYWPL TGFPGTPTQQ EPALHRVGVY LDRGTENVSF YSAVDGVHLH TFSCSSVSRL
RPFFWLSPLA SLVILPVTDR K
//
