UniProt: G1RKW4

Database: UniProt
Entry: G1RKW4_NOMLE

LinkDB:  G1RKW4_NOMLE 
Original site:  G1RKW4_NOMLE

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Ontology (2)   
   GO (2)   
Gene (3)   
   ENSEMBL-UP (3)   
DNA sequence (6)   
   EMBL (6)   
Protein domain (13)   
   InterPro (5)   
   Pfam (3)   
   PROSITE (3)   
   SMART (2)   
All databases (24)   

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ID   G1RKW4_NOMLE            Unreviewed;       278 AA.
AC   G1RKW4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Ankyrin repeat and SOCS box containing 13 {ECO:0000313|Ensembl:ENSNLEP00000013871.1};
GN   Name=ASB13 {ECO:0000313|Ensembl:ENSNLEP00000013871.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000013871.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000013871.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000013871.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC       {ECO:0000256|ARBA:ARBA00005949}.
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DR   EMBL; ADFV01175612; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01175613; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01175614; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01175615; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01175616; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01175617; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; G1RKW4; -.
DR   STRING; 61853.ENSNLEP00000013871; -.
DR   Ensembl; ENSNLET00000014553.3; ENSNLEP00000013871.1; ENSNLEG00000011408.3.
DR   eggNOG; KOG0504; Eukaryota.
DR   GeneTree; ENSGT00940000160326; -.
DR   HOGENOM; CLU_000134_4_2_1; -.
DR   InParanoid; G1RKW4; -.
DR   OMA; DARNIDC; -.
DR   TreeFam; TF331945; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000001073; Chromosome 9.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd03729; SOCS_ASB13; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 1.10.750.20; SOCS box; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR037334; ASB13_SOCS.
DR   InterPro; IPR001496; SOCS_box.
DR   InterPro; IPR036036; SOCS_box-like_dom_sf.
DR   PANTHER; PTHR24136:SF31; ANKYRIN REPEAT AND SOCS BOX CONTAINING 13; 1.
DR   PANTHER; PTHR24136; SOWAH (DROSOPHILA) HOMOLOG; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF07525; SOCS_box; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 6.
DR   SMART; SM00969; SOCS_box; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF158235; SOCS box-like; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 5.
DR   PROSITE; PS50088; ANK_REPEAT; 6.
DR   PROSITE; PS50225; SOCS; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          18..50
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          51..83
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          84..112
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          116..148
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          149..181
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          181..213
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          232..278
FT                   /note="SOCS box"
FT                   /evidence="ECO:0000259|PROSITE:PS50225"
SQ   SEQUENCE   278 AA;  29974 MW;  5B8E6BB211C85284 CRC64;
     MEPRAADGCF LGDVGFWVER TPVHEAAQRG ESLQLQQLIE SGACVNQVTV DSITPLHAAS
     LQGQVRCVQL LLAAGAQVDA RNIDGSTPLC DACASGSIEC VKLLLSYGAK VNPPLYTASP
     LHEACMSGSS ECVRLLIDVG ANLEAHDCHF GTPLHVACAR EHLDCVKVLL NAGANVNAAK
     LHETALHHAA KVKNVDLIEM LIEFGGNIYA RDNRGKKPSD YTWSSSAPAK CLEYYEKTPL
     TLSQLCRVSL RKATGVRGLE KIAKLNIPPR LIDYLSYN
//

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