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Database: UniProt
Entry: G1RL37_NOMLE
LinkDB: G1RL37_NOMLE
Original site: G1RL37_NOMLE 
ID   G1RL37_NOMLE            Unreviewed;      1115 AA.
AC   G1RL37;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   25-OCT-2017, entry version 44.
DE   SubName: Full=Transient receptor potential cation channel subfamily A member 1 {ECO:0000313|Ensembl:ENSNLEP00000013944};
GN   Name=TRPA1 {ECO:0000313|Ensembl:ENSNLEP00000013944};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
OS   leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hylobatidae; Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000013944};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000013944}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000013944}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSNLEP00000013944}.
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DR   EMBL; ADFV01083900; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01083901; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01083902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01083903; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 61853.ENSNLEP00000013944; -.
DR   Ensembl; ENSNLET00000014628; ENSNLEP00000013944; ENSNLEG00000011456.
DR   eggNOG; KOG0510; Eukaryota.
DR   eggNOG; COG0666; LUCA.
DR   GeneTree; ENSGT00900000140877; -.
DR   InParanoid; G1RL37; -.
DR   OMA; YYIEYNF; -.
DR   OrthoDB; EOG091G01BG; -.
DR   TreeFam; TF317264; -.
DR   Proteomes; UP000001073; Unplaced.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0015278; F:calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0097604; F:temperature-gated cation channel activity; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   CDD; cd00204; ANK; 4.
DR   Gene3D; 1.25.40.20; -; 6.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR030288; TRPA1/painless.
DR   PANTHER; PTHR24190; PTHR24190; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 5.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 14.
DR   SUPFAM; SSF48403; SSF48403; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 8.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001073};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    716    736       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    802    820       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    826    846       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    866    888       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    937    961       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       67    575       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT      160    192       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      234    266       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      304    336       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      337    369       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      408    440       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      441    473       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      477    502       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      543    575       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
SQ   SEQUENCE   1115 AA;  127084 MW;  9F2D32D2553C992E CRC64;
     MKRSLRKMWR PGEKKEPQGV VYEDVPDDTE DCKESLKVVF EGSAYGLQNV NKQKKLKRCD
     DMDTFFLHYA AAEGQIELME KITRDSSLEV LHEMDDYGNT PLHVKKTKLK AVLLSRGANP
     NLRNFNMMAP LHIAVQGMNN EVMKVLLEHR TIDVNLEGEN GNTAVIVACT TNNSEALQIL
     LNKGAKPCKS NKWGCFPIHQ AAFSGSKECM EIILRFGEEH GYSRQLHINF MNNGKATPLH
     LAVQNGDLEM IKMCLDNGAQ IDPMEKGRCT AIHFAATQGA TEIVKLMISS YSGSVDIVNT
     TDGCHETMLH RASLFDHHEL ADYLISVGAD INKIDSEGRS PLILATASAS WNIVNLLLSK
     GAQVDIKDNF GRNFLHLTVQ QPYGLKNLRP EFMQMQQIKQ LVMDEDNDGC TPLHYACRQG
     GPGSVNNLLG FNVSIHSKSK DKKSPLHFAA SYGRINTCQR LLQDISDTRL LNEGDLHGMT
     PLHLAAKNGH DKVVQLLLKK GALFLSDHNG WTALHHASMG GYTQTMKVIL DTNLKCTDRL
     DEDGNTALHF AAREGHAKAV ALLLSHNADI VLNKQQASFL HLALHNKRKE VVLTIIRSKR
     WDECLKVFSH NSPGNKCPIT EMIEYLPECM KVLLDFCMLH STEDKSCRDY YIEYNFKYLQ
     CPLEFAKKSP TQDVIYEPLT ALNAMVQNNR IELLNHPVCK EYLLMKWLAY GFRAHMMNLG
     SYCLGLIPMT ILVVNIKPGM AFNSTGIINE TSDHSEILDT TNSYLIKTCM ILVFLSSIFG
     YCKEAGQIFQ QKRNYFMDMN NVFEWIIYTT GIIFVLPLFV EIPAHLQWQC GAIAVYFYWM
     NFLLYLQRFE NCGIFIVMLE VILKTLLRSM VVFVFLLLAF GLSFYILLNL QDPFSSPLLS
     IIQTFSMMLG DINYRESFLE PYLRNELAHP VLSFTQLVSF TIFVPIVLMN LLIGLAVGDI
     AEVQKHASLK RIAMQVELHT SLEKKLPLWF LRKVDQKSTI VYPNKPRSGG MLFHIFCFLF
     CNGEIRQEIP NADKSLEMEI LKQKYRLKDL TFLLEKQHEL IKLIIQKMEI ISETEDEDSH
     CSFQDRFKKE QMEQRNSRWN TVLRAVKEKT HHLEP
//
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