ID G1RNT5_NOMLE Unreviewed; 226 AA.
AC G1RNT5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Phospholipid phosphatase 5 {ECO:0000313|Ensembl:ENSNLEP00000014899.2};
GN Name=PLPP5 {ECO:0000313|Ensembl:ENSNLEP00000014899.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000014899.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000014899.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000014899.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000256|ARBA:ARBA00008816}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01051312; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01051313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003269634.1; XM_003269586.1.
DR AlphaFoldDB; G1RNT5; -.
DR Ensembl; ENSNLET00000015644.3; ENSNLEP00000014899.2; ENSNLEG00000012268.3.
DR eggNOG; KOG3030; Eukaryota.
DR GeneTree; ENSGT00940000159772; -.
DR HOGENOM; CLU_021458_5_4_1; -.
DR TreeFam; TF323722; -.
DR UniPathway; UPA00085; -.
DR Proteomes; UP000001073; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03390; PAP2_containing_1_like; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; LIPID PHOSPHATE PHOSPHATASE; 1.
DR PANTHER; PTHR10165:SF87; PHOSPHOLIPID PHOSPHATASE 5; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..216
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
SQ SEQUENCE 226 AA; 25322 MW; 8D56E7B201E58EBB CRC64;
MGKAAAAAAV AFGAEVCVRL ALFAAFLVTE LLPPFQRLIQ PEEMWLYRNP YVEAEYFPTK
PMFVIAFLSP LSLIFLAKFL KKADTRDSRQ ACLAASLALA LNGVFTNTIK LIVGRPRPDF
FYRCFPDGLA HSDLMCTGDK DVVNEGRKSF PSGHSSFAFA GLAFASFYLA GKLHCFTPQG
RGKSWRFCAF LSPLLFAAVI ALSRTCDYKH HWQGPFKWQK WVDEQQ
//
