ID G1RQ25_NOMLE Unreviewed; 581 AA.
AC G1RQ25;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Caseinolytic mitochondrial matrix peptidase chaperone subunit X {ECO:0000313|Ensembl:ENSNLEP00000015339.2};
GN Name=CLPX {ECO:0000313|Ensembl:ENSNLEP00000015339.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000015339.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000015339.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000015339.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01035763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01035764; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01035765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01035766; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01035767; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1RQ25; -.
DR STRING; 61853.ENSNLEP00000015339; -.
DR Ensembl; ENSNLET00000016115.3; ENSNLEP00000015339.2; ENSNLEG00000012633.3.
DR eggNOG; KOG0745; Eukaryota.
DR GeneTree; ENSGT00390000017625; -.
DR HOGENOM; CLU_014218_0_1_1; -.
DR InParanoid; G1RQ25; -.
DR OMA; ICDCNSL; -.
DR TreeFam; TF312884; -.
DR Proteomes; UP000001073; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0009841; C:mitochondrial endopeptidase Clp complex; IEA:Ensembl.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:Ensembl.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:Ensembl.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0016504; F:peptidase activator activity; IEA:Ensembl.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:Ensembl.
DR CDD; cd19497; RecA-like_ClpX; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR004487; Clp_protease_ATP-bd_su_ClpX.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00382; clpX; 1.
DR PANTHER; PTHR48102:SF7; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48102; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 233..384
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 457..551
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 68..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..561
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 63422 MW; E8857629D331A423 CRC64;
MPSCGACTCG AAAARLITSS LASAQRGISG GRIRMSVLGR LGTFETQILR RAPLRSFTET
PAYFASKDGI SKDGSGDGNK KSASEGSSKK SGSGNSGKGG NQLRCPKCGD LCTHVETFVI
YNYLDKYVVG QSFAKKVLSV AVYNHYKRIY NNIPANLRQQ AEVEKQTSLT PRELEIRRRE
DEYRFTKLLQ IAGISPHGNA LGASMQQQVN QQIPQEKRGG EVLDSSHDDI KLEKSNILLL
GPTGSGKTLL AQTLAKCLDV PFAICDCTTL TQAGYVGEDI ESVIAKLLQD ANYNVEKAQQ
GIVFLDEVDK IGSVPGIHQL RDVGGEGVQQ GLLKLLEGTI VNVPEKNSRK LRGETVQVDT
TNILFVASGA FNGLDRIISR RKNEKYLGFG TPSNLGKGRR AAAAADLANR SGESNTHQDI
EEKDRLLRHV EARDLIEFGM IPEFVGRLPV VVPLHSLDEK TLVQILTEPR NAVIPQYQAL
FSMDKCELNV TEDALKAIAR LALERKTGAR GLRSIMEKLL LEPMFEVPNS DIVCVEVDKE
VVEGKKEPGY IRAPTKDSSE EEYDSGVEEE GWPRQADAAN S
//
