ID G1RV35_NOMLE Unreviewed; 566 AA.
AC G1RV35;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Ring finger protein 220 {ECO:0000313|Ensembl:ENSNLEP00000017112.2};
GN Name=RNF220 {ECO:0000313|Ensembl:ENSNLEP00000017112.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000017112.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000017112.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000017112.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01109033; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01109042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003278688.1; XM_003278640.2.
DR RefSeq; XP_012366897.1; XM_012511443.1.
DR AlphaFoldDB; G1RV35; -.
DR STRING; 61853.ENSNLEP00000017112; -.
DR Ensembl; ENSNLET00000017973.3; ENSNLEP00000017112.2; ENSNLEG00000014047.3.
DR GeneID; 100601355; -.
DR KEGG; nle:100601355; -.
DR CTD; 55182; -.
DR eggNOG; ENOG502QR1N; Eukaryota.
DR GeneTree; ENSGT00390000016573; -.
DR HOGENOM; CLU_035321_0_0_1; -.
DR InParanoid; G1RV35; -.
DR OMA; PTCDAKI; -.
DR OrthoDB; 12276at2759; -.
DR TreeFam; TF324716; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005652; C:nuclear lamina; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR GO; GO:0003358; P:noradrenergic neuron development; IEA:Ensembl.
DR GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
DR GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR CDD; cd16563; RING-HC_RNF220; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031824; RNF220_mid.
DR InterPro; IPR040178; RNF220_RING.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13459:SF3; E3 UBIQUITIN-PROTEIN LIGASE RNF220; 1.
DR PANTHER; PTHR13459; UNCHARACTERIZED; 1.
DR Pfam; PF15926; RNF220; 2.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 514..553
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 277..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 62793 MW; 05E2944FD32BFDE4 CRC64;
MDLHRAAFKM ENSSYLPNPL ASPALMVLAS TAEASRDASI PCQQPRPFGV PVSVDKDVHI
PFTNGSYTFA SMYHRQGGVP GTFANRDFPP SLLHLHPQFA PPNLDCTPIS MLNHSGVGAF
RPFASTEDRE SYQSAFTPAK RLKNCHDTES PHLRFSDADG KEYDFGTQLP SSSPGSLKVD
DTGKKIFAVS GLISDREASS SPEDRNDRCK KKAAALFDSQ APICPICQVL LRPSELQEHM
EQELEQLAQL PSSKNSLLKD AMAPGTPKSL LLSASIKREG ESPTASPHPS ATDDLHHSDR
YQTFMRVRAN RQTRLNARIG KMKRRKQDEG QREGSCMAED DAVDIEHENN NRFEEYEWCG
QKRIRATTLL EGGFRGSGFI MCSGKENPDS DADLDVDGDD TLEYGKPQYT EADVIPCTGE
EPGEAKEREA LRGAVLNGGP PSTRITPEFS KWASDEMPST SNGESSKQEA MQKTCKNSDI
EKITEDSAVT TFEALKARVR ELERQLSRGD RYKCLICMDS YSMPLTSIQC WHVHCEECWL
RTLGAKKLCP QCNTITAPGD LRRIYL
//
