ID G1RWS0_NOMLE Unreviewed; 216 AA.
AC G1RWS0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=RAB2B, member RAS oncogene family {ECO:0000313|Ensembl:ENSNLEP00000017697.1};
GN Name=RAB2B {ECO:0000313|Ensembl:ENSNLEP00000017697.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000017697.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000017697.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000017697.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR EMBL; ADFV01192004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01192005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01192006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01192007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003260896.1; XM_003260848.3.
DR AlphaFoldDB; G1RWS0; -.
DR SMR; G1RWS0; -.
DR STRING; 61853.ENSNLEP00000017697; -.
DR Ensembl; ENSNLET00000018580.2; ENSNLEP00000017697.1; ENSNLEG00000014534.2.
DR GeneID; 100586355; -.
DR KEGG; nle:100586355; -.
DR CTD; 84932; -.
DR eggNOG; KOG0098; Eukaryota.
DR GeneTree; ENSGT00940000153886; -.
DR HOGENOM; CLU_041217_23_1_1; -.
DR InParanoid; G1RWS0; -.
DR OMA; RRETFIH; -.
DR OrthoDB; 4819304at2759; -.
DR TreeFam; TF300032; -.
DR Proteomes; UP000001073; Chromosome 22a.
DR GO; GO:0001669; C:acrosomal vesicle; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR GO; GO:0032481; P:positive regulation of type I interferon production; IEA:Ensembl.
DR CDD; cd01866; Rab2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47979; DRAB11-RELATED; 1.
DR PANTHER; PTHR47979:SF50; RAS-RELATED PROTEIN RAB-2B; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT REGION 189..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 216 AA; 24214 MW; 80A73F6D259701D8 CRC64;
MTYAYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMVNI DGKQIKLQIW
DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLTSW LEDARQHSSS NMVIMLIGNK
SDLESRRDVK REEGEAFARE HGLIFMETSA KTACNVEEAF INTAKEIYRK IQQGLFDVHN
EANGIKIGPQ QSISTSVGPS ASQRNSRDIG SNSGCC
//
