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Database: UniProt
Entry: G1RWZ4_NOMLE
LinkDB: G1RWZ4_NOMLE
Original site: G1RWZ4_NOMLE 
ID   G1RWZ4_NOMLE            Unreviewed;       974 AA.
AC   G1RWZ4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   25-OCT-2017, entry version 41.
DE   SubName: Full=Transient receptor potential cation channel subfamily C member 5 {ECO:0000313|Ensembl:ENSNLEP00000017771};
GN   Name=TRPC5 {ECO:0000313|Ensembl:ENSNLEP00000017771};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
OS   leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hylobatidae; Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000017771};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000017771}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000017771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSNLEP00000017771}.
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DR   EMBL; ADFV01008303; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008306; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01008312; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003262260.1; XM_003262212.1.
DR   STRING; 61853.ENSNLEP00000017771; -.
DR   Ensembl; ENSNLET00000018658; ENSNLEP00000017771; ENSNLEG00000014606.
DR   GeneID; 100597182; -.
DR   KEGG; nle:100597182; -.
DR   CTD; 7224; -.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   GeneTree; ENSGT00760000119180; -.
DR   InParanoid; G1RWZ4; -.
DR   KO; K04968; -.
DR   OMA; GFNEYVH; -.
DR   OrthoDB; EOG091G029I; -.
DR   TreeFam; TF313147; -.
DR   Proteomes; UP000001073; Unplaced.
DR   GO; GO:0034704; C:calcium channel complex; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005461; TRPC5_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF24; PTHR10117:SF24; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   PRINTS; PR01646; TRPCHANNEL5.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001073};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    327    351       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    363    382       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    402    419       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    440    460       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    480    499       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    520    542       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    599    621       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       38    118       ANK_REP_REGION. {ECO:0000259|Pfam:
FT                                PF12796}.
FT   DOMAIN      176    238       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      376    635       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   974 AA;  111549 MW;  E1003DF960F340F7 CRC64;
     MAQLYYKKVN YSPYRDRIPL QIVRAETELS AEEKAFLNAV EKGDYATVKQ ALQEAEIYYN
     VNINCMDPLG RSALLIAIEN ENLEIMELLL NHSVYVGDAL LYAIRKEVVG AVELLLSYRR
     PSGEKQVPTL MMDTQFSEFT PDITPIMLAA HTNNYEIIKL LVQKRVTIPR PHQIRCNCVE
     CVSSSEVDSL RHSRSRLNIY KALASPSLIA LSSEDPILTA FRLGWELKEL SKVENEFKAE
     YEELSQQCKL FAKDLLDQAR SSRELEIILN HRDDHSEELD PQKYHDLAKL KVAIKYHQKE
     FVAQPNCQQL LATLWYDGFP GWRRKHWVVK LLTCMTIGFL FPMLSIAYLI SPRSNLGLFI
     KKPFIKFICH TASYLTFLFM LLLASQHIVR TDLHVQGPPP TVVEWMILPW VLGFIWGEIK
     EMWDGGFTEY IHDWWNLMDF AMNSLYLATI SLKIVAYVKY NGSRPREEWE MWHPTLIAEA
     LFAISNILSS LRLISLFTAN SHLGPLQISL GRMLLDILKF LFIYCLVLLA FANGLNQLYF
     YYETRAIDEP NNCKGIRCEK QNNAFSTLFE TLQSLFWSVF GLLNLYVTNV KARHEFTEFV
     GATMFGTYNV ISLVVLLNML IAMMNNSYQL IADHADIEWK FARTKLWMSY FDEGGTLPPP
     FNIIPSPKSF LYLGNWFNNT FCPKRDPDGR RRRRNLRSFT ERNADSLIQN QHYQEVIRNL
     VKRYVAAMIR NSKTNEGLTE ENFKELKQDI SSFRYEVLDL LGNRKHPRRS FSTSSTEFSQ
     RDDNNDGSGG ARAKSKSVSF NLGCKKKACH GPPLIRTMPR SSGAQGKSKA ESSSKRSFMG
     PSLKKLGLLF SKFNGHMSEP SSEPMYTISD GIVQQHCMWQ DIRYSQMEKG KAEACSQSEI
     NLSEVELGEV QGAAQSSECP LACSSSLHCA SSICSSNSKL LDSSEDVFET WGEACDLLMH
     KWGDGQEEQV TTRL
//
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