ID G1S9B5_NOMLE Unreviewed; 189 AA.
AC G1S9B5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=High mobility group box 4 {ECO:0000313|Ensembl:ENSNLEP00000022105.1};
GN Name=HMGB4 {ECO:0000313|Ensembl:ENSNLEP00000022105.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000022105.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000022105.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000022105.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01094836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003276450.1; XM_003276402.2.
DR AlphaFoldDB; G1S9B5; -.
DR STRING; 61853.ENSNLEP00000022105; -.
DR Ensembl; ENSNLET00000023223.2; ENSNLEP00000022105.1; ENSNLEG00000018198.2.
DR GeneID; 100603940; -.
DR KEGG; nle:100603940; -.
DR CTD; 127540; -.
DR eggNOG; KOG0381; Eukaryota.
DR GeneTree; ENSGT00940000162735; -.
DR HOGENOM; CLU_082854_0_4_1; -.
DR InParanoid; G1S9B5; -.
DR OMA; MWSAKTD; -.
DR OrthoDB; 1222485at2759; -.
DR TreeFam; TF105371; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21978; HMG-box_HMGB_rpt1; 1.
DR CDD; cd21979; HMG-box_HMGB_rpt2; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR48112:SF7; HIGH MOBILITY GROUP PROTEIN B4; 1.
DR PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS50118; HMG_BOX_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 9..79
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 93..161
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 9..79
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 93..161
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 78..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 189 AA; 22788 MW; A57BD4C421A18A51 CRC64;
MGKEIQLKPK ANVSSYVHFL LNYRNTFKEQ QPNTYVGFKE FSRKCSEEWR SISKHEKAKY
EALAKVDKAR YQEEMMNYVG KRKKRRKRDP QAPRRPPSSF LLFCQDHYAQ LKRENPNWSV
VQVAKATGEM WSTTTDLEKH PYEQRAALLR AKYFEELELY RKQHKQCNAR KKYRMSARNR
CRGKRVRQS
//
