ID G1S9N8_NOMLE Unreviewed; 307 AA.
AC G1S9N8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Solute carrier family 25 member 53 {ECO:0000313|Ensembl:ENSNLEP00000022229.1};
GN Name=SLC25A53 {ECO:0000313|Ensembl:ENSNLEP00000022229.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000022229.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000022229.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000022229.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; ADFV01007938; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003262184.1; XM_003262136.2.
DR AlphaFoldDB; G1S9N8; -.
DR STRING; 61853.ENSNLEP00000022229; -.
DR Ensembl; ENSNLET00000023350.2; ENSNLEP00000022229.1; ENSNLEG00000018325.2.
DR GeneID; 100601367; -.
DR KEGG; nle:100601367; -.
DR CTD; 401612; -.
DR eggNOG; KOG1519; Eukaryota.
DR GeneTree; ENSGT00940000161713; -.
DR HOGENOM; CLU_061821_1_0_1; -.
DR InParanoid; G1S9N8; -.
DR OMA; WPVLLRN; -.
DR OrthoDB; 46552at2759; -.
DR TreeFam; TF314192; -.
DR Proteomes; UP000001073; Chromosome X.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR46131; SD08549P; 1.
DR PANTHER; PTHR46131:SF5; SOLUTE CARRIER FAMILY 25 MEMBER 53; 1.
DR Pfam; PF00153; Mito_carr; 2.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 25..105
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 112..202
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 307 AA; 34581 MW; EC3D617DEF804F1B CRC64;
MGEQNHSPRK ELQHRTRAEA PGKESWHSQA YALGAVSNFM STFLTFPIYK VVFRQQIHAM
AVSEAVRQLW HEGPQYFYRG IYPPLLSKTL QGTLLFGTYD SLLCFLSPVG PHTLGHRWAA
GLMSGVVEAV ALSPFERVQN VLQDGRKQAR FPSTFSILKE FNSYGLWGRL SLGYYRGFWP
VLARNSLGSA LYFSFKDPIQ DGLAEQGLPH WVPALVSGSV NGTITCLVLY PLIVLVANMQ
SHIGWQNMPS LWASAQDVWN TRGRKLLLIY RGGSLVILRS SVTWGLTTAI HDFLQRKSHS
RKELKTD
//
