ID G1TDK6_RABIT Unreviewed; 358 AA.
AC G1TDK6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Kelch domain containing 2 {ECO:0000313|Ensembl:ENSOCUP00000014934.3};
GN Name=KLHDC2 {ECO:0000313|Ensembl:ENSOCUP00000014934.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000014934.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000014934.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000014934.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000014934.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000014934.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; AAGW02050034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1TDK6; -.
DR Ensembl; ENSOCUT00000017376.3; ENSOCUP00000014934.3; ENSOCUG00000017378.3.
DR eggNOG; KOG0379; Eukaryota.
DR GeneTree; ENSGT00940000157150; -.
DR HOGENOM; CLU_042804_0_0_1; -.
DR TreeFam; TF314081; -.
DR Proteomes; UP000001811; Chromosome 17.
DR Bgee; ENSOCUG00000017378; Expressed in blood and 16 other cell types or tissues.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR PANTHER; PTHR46228; KELCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46228:SF3; KELCH DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF13418; Kelch_4; 3.
DR SUPFAM; SSF117281; Kelch motif; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 358 AA; 40701 MW; 6EE26700B13106AC CRC64;
MAEGNEDLRA DDLPGPAFEG YEAMELACPA ERSGHVAVSD GRHMFVWGGY KSNQVRGLYD
FYLPREELWI YNMETGRWKK INTEGDVPPS MSGSCAVCVD RVLYLFGGHH SRGNTNKFYM
LDSRSTDRVL QWERIDCQGI PPSSKDKLGV WVYKNKLIFF GGYGYLPEDK VLGTFEFDET
SFWNSSHPRG WNDHVHILDT ETFTWSQPVT AGKAPSPRAA HACATVGNKG FVFGGRYRDA
RMNDLHYLNL DTWEWTELIP QGICPVGRSW HSLTPVSSDH LFLFGGFTTD KQPLSDAWTY
CISKNEWIQF NHPYTEKPRL WHTACASDEG EVIVFGGCAN NLLVHHRAAK LRSSHLFQ
//
