ID G1TY38_RABIT Unreviewed; 481 AA.
AC G1TY38;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Interferon induced protein with tetratricopeptide repeats 5 {ECO:0008006|Google:ProtNLM};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000021998.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000021998.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000021998.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000021998.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000021998.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IFIT family.
CC {ECO:0000256|ARBA:ARBA00038336}.
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DR EMBL; AAGW02036398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02036399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02036400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1TY38; -.
DR Ensembl; ENSOCUT00000025593.2; ENSOCUP00000021998.2; ENSOCUG00000005445.3.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00950000182946; -.
DR HOGENOM; CLU_043482_1_0_1; -.
DR TreeFam; TF342671; -.
DR Proteomes; UP000001811; Chromosome 18.
DR Bgee; ENSOCUG00000005445; Expressed in blood and 18 other cell types or tissues.
DR ExpressionAtlas; G1TY38; baseline.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10271; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS; 1.
DR PANTHER; PTHR10271:SF28; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 248..281
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 337..370
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 434..467
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 481 AA; 55399 MW; E6559629191C872C CRC64;
MSDISKDSLK AILLELECHF TWNLLKKDID LFEVEDTIGQ QLEFLTTKSR LALYNLLAYV
KHLKGQNKDA LKCLEQAEAI IQQEHADEKE VRSLVTWGNY AWVSYRMGRF EEVQKYIDQV
GNVCKKLSSP SNYKLQCPAI DCEKGWALLK FGGKYYQKAK VAFEKALEAE PDNPEFNIGY
AITVYRLDNF DEEGSIKSFS LGPLRKAVAL NPHDTYIKVF LALKLQDVHA EAEGERYIEE
ILEQTSQPYV LRYAAKFYRR KKSWDKALQL LKKALEATPN SSFLHHQMGL CYRAQMIQIK
KATRNRPKGK DKLKVDELIA SAIFHFRAAV EQDSMFVFAY LDLASMYAEG GQHRNAEDIF
QKALCLEHIT DDHKQQIHYH YGRFQEFHRK SDYAAIHHYL EALKVKHGSS LHMKLTSALK
KLATKRLCHN ASDVQSLSAL GFVYKLEGDK RQAAAYYQKA QKIDPENAEF LTALCELQLS
I
//
